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- W2407303816 abstract "Background : HLA-B40 includes two serologic specificities, B60 and B61, and at least 45 alleles of the B*40 group have been identified. B40 shows a gene frequency of 13.4% (B60 4.5%, B61 8.9%) in Koreans. In this study, the distribution of HLA-B40 alleles and their association with HLA-A, -Cw and -DRB1 alleles were investigated in the Korean population. Methods : A total of 453 healthy unrelated Koreans including 215 parents from 108 families were studied. For all samples, HLA-A, B, C serological typing, HLA-Cw low resolution typing using polymerase chain reaction (PCR)-sequence specific oligonucleotide (SSO) method, and HLA-DRB1 genotyping using PCR-single strand conformation polymorphism (SSCP) method were performed. All of the 112 samples (24.7%) typed as B40 by serology were analyzed for B40 alleles using the PCRSSCP method. Results : Four B40 alleles were detected in the Korean population and their allele frequencies were: B*4001 4.4%, B*4002 5.0%, B*4003 0.4%, and B*4006 3.2%. A significant association (P" @default.
- W2407303816 created "2016-06-24" @default.
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- W2407303816 date "2003-02-01" @default.
- W2407303816 modified "2023-09-26" @default.
- W2407303816 title "Diversity of HLA-A26 Alleles and Haplotypes in Koreans" @default.
- W2407303816 hasPublicationYear "2003" @default.
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