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- W2407315057 abstract "Cyclosporin A (CSA), a potent immunosuppressant with the adverse side effect of nephrotoxicity, inhibited cell growth of pig kidney tubule cells (LLC-PK1) in culture. CSA (10(-5) M) also induced intense cytoplasmic vacuolation and the formation of dense granules. At the same concentration an analogue of CSA, cyclosporin G, had much less effect. This cell line may prove useful for revealing the mechanism of CSA-nephrotoxicity and testing the nephrotoxic potential of new analogues of cyclosporine." @default.
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- W2407315057 date "1987-05-01" @default.
- W2407315057 modified "2023-09-23" @default.
- W2407315057 title "Effects of cyclosporin A on a kidney epithelial cell line (LLC-PK1)." @default.
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