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- W2407567635 abstract "We review behavioral and biometrical genetic research aimed at characterizing the nature of the familial aggregation of adolescent substance use and abuse. Twin and adoption studies have shown that genetic factors contribute to individual differences in adolescent substance use phenotypes. These studies have also documented the importance of the shared environment. Biometrical analyses of large samples of twins show that the contributions of genetic and shared environmental factors to substance use phenotypes change markedly between adolescence and early adulthood. The importance of genetic influence increases with age as the importance of shared environmental influences declines. Although only a small number of relevant genetic variants have been identified at this time, they show a similar pattern of increasing association with substance use behavior with age. A major question continues to be how genetic and environmental factors operate jointly to influence the development of complex behavioral phenotypes such as substance use." @default.
- W2407567635 created "2016-06-24" @default.
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- W2407567635 date "2016-04-07" @default.
- W2407567635 modified "2023-10-16" @default.
- W2407567635 title "Behavioral Genetics of Adolescent Substance Use and Abuse" @default.
- W2407567635 doi "https://doi.org/10.1093/oxfordhb/9780199735662.013.013" @default.
- W2407567635 hasPublicationYear "2016" @default.
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