Matches in SemOpenAlex for { <https://semopenalex.org/work/W2407778830> ?p ?o ?g. }
- W2407778830 endingPage "634" @default.
- W2407778830 startingPage "625" @default.
- W2407778830 abstract "Purpose To evaluate the long-term biochemical, clinical, and recurrence outcomes of radiofrequency (RF) ablation in treating primary aldosteronism due to aldosterone-producing adenoma (APA). Materials and Methods Institutional review board approval and written informed consent were obtained. The use of computed tomographically (CT) guided percutaneous RF ablation was evaluated in 36 patients (19 men; mean age ± standard deviation, 52.1 years ± 10.4) with APA (17 right and 19 left side; mean size, 15.5 mm ± 5.0). Primary aldosteronism was confirmed by using the oral sodium-loading test. After RF ablation, CT images, aldosterone-to-renin ratio (ARR), serum potassium level, and blood pressure control were assessed at 3 months and at the latest follow-up examination. Long-term treatment success was defined as normalization of ARR at the latest assessment. Comparison of ARR, potassium, and blood pressure levels before and after RF ablation was performed by using the Wilcoxon signed-rank test. Results Primary technical success was achieved in 33 (92%) patients who underwent a single RF ablation session. Secondary technical success was achieved in three (8%) patients who required a second RF ablation. At 3-month follow-up, primary aldosteronism was resolved in 33 (92%) patients, with a starting median ARR of 8583 pmol/L per µg/(L · h) that normalized to 97 pmol/L per µg/(L · h) (P < .01). Mean serum potassium levels increased from 2.6 mmol/L ± 0.4 to 4.0 mmol/L ± 0.3 (P = .01). At long-term follow-up (mean, 6.2 years ± 2.5), treatment success was maintained in 33 patients (92%), all of whom had ARRs in the normal range (P < .01). The long-term recurrence rate was 0%. Hypokalemia was resolved in all patients (2.6 mmol/L ± 0.4 to 4.1 mmol/L ± 0.3, P = .01). Hypertension was resolved in 13 (36%) patients, and its control was improved in seven (19%) patients. One (3%) patient had major complications and six (17%) had minor complications. Conclusion CT-guided RF ablation is an effective treatment for APA, with high sustainable long-term treatment success. It may serve as a justifiable treatment alternative to surgery and medical therapy for APA. © RSNA, 2016" @default.
- W2407778830 created "2016-06-24" @default.
- W2407778830 creator A5022902793 @default.
- W2407778830 creator A5035287101 @default.
- W2407778830 creator A5037092932 @default.
- W2407778830 creator A5043812892 @default.
- W2407778830 creator A5051149404 @default.
- W2407778830 creator A5065258642 @default.
- W2407778830 creator A5076758172 @default.
- W2407778830 creator A5079884638 @default.
- W2407778830 date "2016-11-01" @default.
- W2407778830 modified "2023-09-29" @default.
- W2407778830 title "Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation—Long-term Results and Recurrence Rate" @default.
- W2407778830 cites W1518920873 @default.
- W2407778830 cites W1600554837 @default.
- W2407778830 cites W160213282 @default.
- W2407778830 cites W1967868608 @default.
- W2407778830 cites W1969565878 @default.
- W2407778830 cites W1969942274 @default.
- W2407778830 cites W1971153308 @default.
- W2407778830 cites W1975847524 @default.
- W2407778830 cites W1992509588 @default.
- W2407778830 cites W1994444064 @default.
- W2407778830 cites W2001486600 @default.
- W2407778830 cites W2001601001 @default.
- W2407778830 cites W2013908283 @default.
- W2407778830 cites W2028420253 @default.
- W2407778830 cites W2031576950 @default.
- W2407778830 cites W2035037852 @default.
- W2407778830 cites W2041836061 @default.
- W2407778830 cites W2052253876 @default.
- W2407778830 cites W2057961394 @default.
- W2407778830 cites W2061429541 @default.
- W2407778830 cites W2065675215 @default.
- W2407778830 cites W2076941575 @default.
- W2407778830 cites W2077889045 @default.
- W2407778830 cites W2087855842 @default.
- W2407778830 cites W2104571780 @default.
- W2407778830 cites W2110613492 @default.
- W2407778830 cites W2115363428 @default.
- W2407778830 cites W2117303303 @default.
- W2407778830 cites W2117574100 @default.
- W2407778830 cites W2132044241 @default.
- W2407778830 cites W2141619493 @default.
- W2407778830 cites W2155103807 @default.
- W2407778830 cites W2156903075 @default.
- W2407778830 cites W2415131153 @default.
- W2407778830 cites W3021753598 @default.
- W2407778830 cites W4211016798 @default.
- W2407778830 doi "https://doi.org/10.1148/radiol.2016152277" @default.
- W2407778830 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27232638" @default.
- W2407778830 hasPublicationYear "2016" @default.
- W2407778830 type Work @default.
- W2407778830 sameAs 2407778830 @default.
- W2407778830 citedByCount "33" @default.
- W2407778830 countsByYear W24077788302017 @default.
- W2407778830 countsByYear W24077788302018 @default.
- W2407778830 countsByYear W24077788302019 @default.
- W2407778830 countsByYear W24077788302020 @default.
- W2407778830 countsByYear W24077788302021 @default.
- W2407778830 countsByYear W24077788302022 @default.
- W2407778830 countsByYear W24077788302023 @default.
- W2407778830 crossrefType "journal-article" @default.
- W2407778830 hasAuthorship W2407778830A5022902793 @default.
- W2407778830 hasAuthorship W2407778830A5035287101 @default.
- W2407778830 hasAuthorship W2407778830A5037092932 @default.
- W2407778830 hasAuthorship W2407778830A5043812892 @default.
- W2407778830 hasAuthorship W2407778830A5051149404 @default.
- W2407778830 hasAuthorship W2407778830A5065258642 @default.
- W2407778830 hasAuthorship W2407778830A5076758172 @default.
- W2407778830 hasAuthorship W2407778830A5079884638 @default.
- W2407778830 hasBestOaLocation W24077788301 @default.
- W2407778830 hasConcept C126322002 @default.
- W2407778830 hasConcept C126838900 @default.
- W2407778830 hasConcept C126894567 @default.
- W2407778830 hasConcept C2777377203 @default.
- W2407778830 hasConcept C2777428134 @default.
- W2407778830 hasConcept C2778525890 @default.
- W2407778830 hasConcept C2778902805 @default.
- W2407778830 hasConcept C2778914232 @default.
- W2407778830 hasConcept C2780233176 @default.
- W2407778830 hasConcept C2989005 @default.
- W2407778830 hasConcept C71924100 @default.
- W2407778830 hasConcept C84393581 @default.
- W2407778830 hasConceptScore W2407778830C126322002 @default.
- W2407778830 hasConceptScore W2407778830C126838900 @default.
- W2407778830 hasConceptScore W2407778830C126894567 @default.
- W2407778830 hasConceptScore W2407778830C2777377203 @default.
- W2407778830 hasConceptScore W2407778830C2777428134 @default.
- W2407778830 hasConceptScore W2407778830C2778525890 @default.
- W2407778830 hasConceptScore W2407778830C2778902805 @default.
- W2407778830 hasConceptScore W2407778830C2778914232 @default.
- W2407778830 hasConceptScore W2407778830C2780233176 @default.
- W2407778830 hasConceptScore W2407778830C2989005 @default.
- W2407778830 hasConceptScore W2407778830C71924100 @default.
- W2407778830 hasConceptScore W2407778830C84393581 @default.
- W2407778830 hasIssue "2" @default.
- W2407778830 hasLocation W24077788301 @default.