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- W2407778893 abstract "Hepatitis C virus (HCV) genotype is the key to prediction of the therapeutic effect of combination therapy of pegylated interferon and ribavirin. HCV grouping test, which is used as a routine testing method, is simple and practical, but the results are sometimes not conclusive. In order to cope with such cases, we have adopted a direct sequencing method since 2003. This paper summarizes the HCV genotype test results obtained between 2003 and 2011. The results showed that the genotypes of 129 of 255 specimens which were not determined by the HCV grouping test were all successfully determined by the direct sequencing method. In the serotype determined samples the concordance rate with direct sequencing was 99.0% in HCV serotype 1 and 88.0% in HCV serotype 2. These findings suggest that the direct sequencing method is useful to determine the genotypes of specimens when untypeable with the HCV grouping test." @default.
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- W2407778893 date "2012-10-01" @default.
- W2407778893 modified "2023-09-23" @default.
- W2407778893 title "[Usefulness of hepatitis C virus (HCV) genotype test using direct sequencing of 5' untranslated region--application from 2003 to 2011]." @default.
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