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- W2407815087 abstract "We studied isolated bovine mesenteric lymphatics to investigate the pharmacological properties of the postjunctional-adrenoceptors. Rings of the lymph vessels were mounted for isometric tension recording in organ chambers filled with Krebs-Ringer bicarbonate solution. The lymph vessels contracted when exposed to phenylephrine and clonidine. The relative sensitivity of the vessels to clonidine was larger than to phenylephrine. Yohimbine was a competitive antagonist against phenylephrine and clonidine in the lymph vessels. Prazosin caused a parallel shift to the right of the dose-response curve to phenylephrine, and not to clonidine in the vessels. The Schild's plot for yohimbine in the lymph vessels suggests that the presence of both alpha 1- and alpha 2-like adrenoceptors on lymphatic smooth muscle cells." @default.
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- W2407815087 date "1983-02-01" @default.
- W2407815087 modified "2023-09-23" @default.
- W2407815087 title "[Characteristics of alpha adrenoceptors of lymphatics and their physiological significance]." @default.
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