Matches in SemOpenAlex for { <https://semopenalex.org/work/W2407897922> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2407897922 endingPage "41" @default.
- W2407897922 startingPage "39" @default.
- W2407897922 abstract "The short-term prognosis of the typical, post-enteropathic form of infantile HUS is usually good, with a complete recovery of renal function. However, the extent of the renal damage observed on some biopsies may raise concern for the long-term prognosis. Therefore, we studied the outcome of 29 patients affected with classical HUS in infancy or early childhood and followed-up for 15-28 years (m = 18 yrs). Initial renal symptoms ranged from a moderate renal failure with normal diuresis to a 12-day anuria: 21 children had to be treated by peritoneal dialysis. Twenty-five patients underwent a renal biopsy shortly after recovery: lesions of glomerular thrombotic microangiopathy (TMA) were found in 14 patients, and patchy cortical necrosis was diagnosed in the other 11. At latest examination 10 patients had no renal abnormality, 12 had residual renal symptoms (hypertension in 7, proteinuria in 4 and midly reduced GFR in 1), 3 were in chronic renal failure (CRF), and 4 had reached end-stage renal failure (ESRF) 16-24 years after onset; 2 of these latter 4 had a normal GFR at 10-year examination. The long-term evolution was not correlated with the initial clinical severity but appeared well correlated with the extent of the histological damage: 10 of the 11 patients with cortical necrosis have either ESRF (4), CRF (3) or renal sequelae (3), and 4 of the 5 patients with TMA involving more than 50% of glomeruli present with moderate sequelae, whereas the 9 patients with TMA involving less than 50% of glomeruli are symptom-free or have mild sequelae. Thus, the risk of renal failure 20 years after a seemingly cured childhood HUS is not negligible, and renal histology is the best indicator of long-term prognosis." @default.
- W2407897922 created "2016-06-24" @default.
- W2407897922 creator A5029494277 @default.
- W2407897922 creator A5031780598 @default.
- W2407897922 creator A5050457860 @default.
- W2407897922 creator A5075326391 @default.
- W2407897922 creator A5076975594 @default.
- W2407897922 date "1996-07-01" @default.
- W2407897922 modified "2023-09-26" @default.
- W2407897922 title "Long-term (15-25 years) outcome of childhood hemolytic-uremic syndrome." @default.
- W2407897922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8832149" @default.
- W2407897922 hasPublicationYear "1996" @default.
- W2407897922 type Work @default.
- W2407897922 sameAs 2407897922 @default.
- W2407897922 citedByCount "35" @default.
- W2407897922 countsByYear W24078979222013 @default.
- W2407897922 countsByYear W24078979222014 @default.
- W2407897922 countsByYear W24078979222015 @default.
- W2407897922 countsByYear W24078979222017 @default.
- W2407897922 countsByYear W24078979222018 @default.
- W2407897922 crossrefType "journal-article" @default.
- W2407897922 hasAuthorship W2407897922A5029494277 @default.
- W2407897922 hasAuthorship W2407897922A5031780598 @default.
- W2407897922 hasAuthorship W2407897922A5050457860 @default.
- W2407897922 hasAuthorship W2407897922A5075326391 @default.
- W2407897922 hasAuthorship W2407897922A5076975594 @default.
- W2407897922 hasConcept C126322002 @default.
- W2407897922 hasConcept C134018914 @default.
- W2407897922 hasConcept C141071460 @default.
- W2407897922 hasConcept C159641895 @default.
- W2407897922 hasConcept C2776422910 @default.
- W2407897922 hasConcept C2777350860 @default.
- W2407897922 hasConcept C2777878052 @default.
- W2407897922 hasConcept C2778653478 @default.
- W2407897922 hasConcept C2779056158 @default.
- W2407897922 hasConcept C2779134260 @default.
- W2407897922 hasConcept C2779561371 @default.
- W2407897922 hasConcept C2779978075 @default.
- W2407897922 hasConcept C2780091579 @default.
- W2407897922 hasConcept C2781087799 @default.
- W2407897922 hasConcept C2781184683 @default.
- W2407897922 hasConcept C54847362 @default.
- W2407897922 hasConcept C555293320 @default.
- W2407897922 hasConcept C71924100 @default.
- W2407897922 hasConcept C90924648 @default.
- W2407897922 hasConceptScore W2407897922C126322002 @default.
- W2407897922 hasConceptScore W2407897922C134018914 @default.
- W2407897922 hasConceptScore W2407897922C141071460 @default.
- W2407897922 hasConceptScore W2407897922C159641895 @default.
- W2407897922 hasConceptScore W2407897922C2776422910 @default.
- W2407897922 hasConceptScore W2407897922C2777350860 @default.
- W2407897922 hasConceptScore W2407897922C2777878052 @default.
- W2407897922 hasConceptScore W2407897922C2778653478 @default.
- W2407897922 hasConceptScore W2407897922C2779056158 @default.
- W2407897922 hasConceptScore W2407897922C2779134260 @default.
- W2407897922 hasConceptScore W2407897922C2779561371 @default.
- W2407897922 hasConceptScore W2407897922C2779978075 @default.
- W2407897922 hasConceptScore W2407897922C2780091579 @default.
- W2407897922 hasConceptScore W2407897922C2781087799 @default.
- W2407897922 hasConceptScore W2407897922C2781184683 @default.
- W2407897922 hasConceptScore W2407897922C54847362 @default.
- W2407897922 hasConceptScore W2407897922C555293320 @default.
- W2407897922 hasConceptScore W2407897922C71924100 @default.
- W2407897922 hasConceptScore W2407897922C90924648 @default.
- W2407897922 hasIssue "1" @default.
- W2407897922 hasLocation W24078979221 @default.
- W2407897922 hasOpenAccess W2407897922 @default.
- W2407897922 hasPrimaryLocation W24078979221 @default.
- W2407897922 hasRelatedWork W1976795742 @default.
- W2407897922 hasRelatedWork W1998834402 @default.
- W2407897922 hasRelatedWork W2106218826 @default.
- W2407897922 hasRelatedWork W2384634414 @default.
- W2407897922 hasRelatedWork W2384860069 @default.
- W2407897922 hasRelatedWork W2396173203 @default.
- W2407897922 hasRelatedWork W2407897922 @default.
- W2407897922 hasRelatedWork W2771165282 @default.
- W2407897922 hasRelatedWork W2794272427 @default.
- W2407897922 hasRelatedWork W3160577430 @default.
- W2407897922 hasVolume "46" @default.
- W2407897922 isParatext "false" @default.
- W2407897922 isRetracted "false" @default.
- W2407897922 magId "2407897922" @default.
- W2407897922 workType "article" @default.