Matches in SemOpenAlex for { <https://semopenalex.org/work/W2407973009> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2407973009 endingPage "7, 42" @default.
- W2407973009 startingPage "605" @default.
- W2407973009 abstract "To detect specifically the localization of thrombus in vivo, we prepared a monoclonal antibody (McAb) SZ-51 specific for an alpha-granule membrane protein (GMP-140) exposed on the surface of activated human platelets. 131I labeled SZ-51 antibody combined preferentially with thrombus induced by thrombin in vitro. Owing to McAb SZ-51 crossreaction with the activated platelets of dogs, thrombi in both femoral artery and vein were prepared and imaged with SPECT in dogs. The ratio of radioactivity between thrombi and blood pool was significantly increased in both arterial and venous thrombus after injection of 131I-SZ-51, especially at the 4th hour. Moreover, the imaging of arterial thrombus is better than that of venous thrombus. However, both arterial and venous thrombi could not be imaged by the injection of 131I-nonimmune IgG. These findings were in agreement with the radioactivity ratios between the removed thrombi and blood 24 hours after injection. Therefore, these results indicate that McAb SZ-51 has the power of detecting thrombi in vivo." @default.
- W2407973009 created "2016-06-24" @default.
- W2407973009 creator A5071405178 @default.
- W2407973009 date "1991-11-01" @default.
- W2407973009 modified "2023-09-25" @default.
- W2407973009 title "[Application of a monoclonal antibody SZ-51 specific for activated human platelets in canine thrombosis imaging]." @default.
- W2407973009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1725498" @default.
- W2407973009 hasPublicationYear "1991" @default.
- W2407973009 type Work @default.
- W2407973009 sameAs 2407973009 @default.
- W2407973009 citedByCount "1" @default.
- W2407973009 countsByYear W24079730092017 @default.
- W2407973009 crossrefType "journal-article" @default.
- W2407973009 hasAuthorship W2407973009A5071405178 @default.
- W2407973009 hasConcept C126322002 @default.
- W2407973009 hasConcept C126838900 @default.
- W2407973009 hasConcept C142724271 @default.
- W2407973009 hasConcept C150903083 @default.
- W2407973009 hasConcept C159654299 @default.
- W2407973009 hasConcept C185592680 @default.
- W2407973009 hasConcept C203014093 @default.
- W2407973009 hasConcept C207001950 @default.
- W2407973009 hasConcept C2778854125 @default.
- W2407973009 hasConcept C2779723990 @default.
- W2407973009 hasConcept C2780868729 @default.
- W2407973009 hasConcept C2781362458 @default.
- W2407973009 hasConcept C3018697912 @default.
- W2407973009 hasConcept C542903549 @default.
- W2407973009 hasConcept C71924100 @default.
- W2407973009 hasConcept C86803240 @default.
- W2407973009 hasConcept C89560881 @default.
- W2407973009 hasConceptScore W2407973009C126322002 @default.
- W2407973009 hasConceptScore W2407973009C126838900 @default.
- W2407973009 hasConceptScore W2407973009C142724271 @default.
- W2407973009 hasConceptScore W2407973009C150903083 @default.
- W2407973009 hasConceptScore W2407973009C159654299 @default.
- W2407973009 hasConceptScore W2407973009C185592680 @default.
- W2407973009 hasConceptScore W2407973009C203014093 @default.
- W2407973009 hasConceptScore W2407973009C207001950 @default.
- W2407973009 hasConceptScore W2407973009C2778854125 @default.
- W2407973009 hasConceptScore W2407973009C2779723990 @default.
- W2407973009 hasConceptScore W2407973009C2780868729 @default.
- W2407973009 hasConceptScore W2407973009C2781362458 @default.
- W2407973009 hasConceptScore W2407973009C3018697912 @default.
- W2407973009 hasConceptScore W2407973009C542903549 @default.
- W2407973009 hasConceptScore W2407973009C71924100 @default.
- W2407973009 hasConceptScore W2407973009C86803240 @default.
- W2407973009 hasConceptScore W2407973009C89560881 @default.
- W2407973009 hasIssue "11" @default.
- W2407973009 hasLocation W24079730091 @default.
- W2407973009 hasOpenAccess W2407973009 @default.
- W2407973009 hasPrimaryLocation W24079730091 @default.
- W2407973009 hasRelatedWork W2005974889 @default.
- W2407973009 hasRelatedWork W2170897550 @default.
- W2407973009 hasRelatedWork W217496567 @default.
- W2407973009 hasRelatedWork W2407058774 @default.
- W2407973009 hasRelatedWork W2407973009 @default.
- W2407973009 hasRelatedWork W2467628983 @default.
- W2407973009 hasRelatedWork W3213643530 @default.
- W2407973009 hasRelatedWork W328538055 @default.
- W2407973009 hasRelatedWork W4283754595 @default.
- W2407973009 hasRelatedWork W63066734 @default.
- W2407973009 hasVolume "71" @default.
- W2407973009 isParatext "false" @default.
- W2407973009 isRetracted "false" @default.
- W2407973009 magId "2407973009" @default.
- W2407973009 workType "article" @default.