FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2408255425> ?p ?o ?g. }

• W2408255425 abstract "Tests of statistical hypotheses concerning treatment effect on the development of hepatocellular foci can be carried out directly on two-dimensional observations made on histologic sections or on estimates of the density and volume of foci in three dimensions. Inferences about differences in the density or size of foci from tests based on two-dimensional observations, however, can be misleading. This is because both the number of focus cross-sections observed in a tissue section and the percent area occupied by foci can be expressed in terms of the number of foci per unit volume of liver tissue and the mean focus size. As a consequence, a treatment difference may be caused by a difference in the density of foci, their average size, or both. Of more serious concern is the possibility that failure to detect a treatment effect may occur not only when there is no treatment effect but also when the density and size of foci differ between treatments in such a way that their product is unchanged. This can happen if the effect of treatment is to increase the number of foci and decrease their average size, or vice versa. A similar difficulty of interpretation is associated with hypothesis tests based on average focus cross-section area. Tests based on estimates of the number of foci per unit volume and mean focus volume allow direct inference about the quantities of interest, but these estimates are unstable because they have large variances. Empirical estimates of statistical power for the Wilcoxon rank sum test and the t-test from data on control rats suggest power may be limited in experiments with group sizes of ten and low observed numbers of focus cross-sections. If hypothesis tests based on estimates of the density and size of foci are to form the basis for a bioassay, then the power of statistical tests used to identify treatment effects should be investigated." @default.
• W2408255425 created "2016-06-24" @default.
• W2408255425 creator A5046453433 @default.
• W2408255425 date "1989-04-01" @default.
• W2408255425 modified "2023-09-23" @default.
• W2408255425 title "Testing Statistical Hypotheses about Rat Liver Foci" @default.
• W2408255425 cites W1983531160 @default.
• W2408255425 cites W1984739634 @default.
• W2408255425 cites W1986993015 @default.
• W2408255425 cites W1992160587 @default.
• W2408255425 cites W2004365540 @default.
• W2408255425 cites W2009789846 @default.
• W2408255425 cites W2012081080 @default.
• W2408255425 cites W2015234075 @default.
• W2408255425 cites W2020686607 @default.
• W2408255425 cites W2023663955 @default.
• W2408255425 cites W2030605602 @default.
• W2408255425 cites W2075289457 @default.
• W2408255425 cites W2088831639 @default.
• W2408255425 cites W2252609745 @default.
• W2408255425 cites W2319267476 @default.
• W2408255425 cites W4229870005 @default.
• W2408255425 doi "https://doi.org/10.1177/0192623389017004103" @default.
• W2408255425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2697938" @default.
• W2408255425 hasPublicationYear "1989" @default.
• W2408255425 type Work @default.
• W2408255425 sameAs 2408255425 @default.
• W2408255425 citedByCount "11" @default.
• W2408255425 countsByYear W24082554252018 @default.
• W2408255425 crossrefType "journal-article" @default.
• W2408255425 hasAuthorship W2408255425A5046453433 @default.
• W2408255425 hasConcept C105795698 @default.
• W2408255425 hasConcept C120665830 @default.
• W2408255425 hasConcept C121332964 @default.
• W2408255425 hasConcept C12868164 @default.
• W2408255425 hasConcept C142724271 @default.
• W2408255425 hasConcept C192209626 @default.
• W2408255425 hasConcept C20556612 @default.
• W2408255425 hasConcept C206041023 @default.
• W2408255425 hasConcept C2776993930 @default.
• W2408255425 hasConcept C33923547 @default.
• W2408255425 hasConcept C62520636 @default.
• W2408255425 hasConcept C65409693 @default.
• W2408255425 hasConcept C71924100 @default.
• W2408255425 hasConcept C87007009 @default.
• W2408255425 hasConcept C96608239 @default.
• W2408255425 hasConceptScore W2408255425C105795698 @default.
• W2408255425 hasConceptScore W2408255425C120665830 @default.
• W2408255425 hasConceptScore W2408255425C121332964 @default.
• W2408255425 hasConceptScore W2408255425C12868164 @default.
• W2408255425 hasConceptScore W2408255425C142724271 @default.
• W2408255425 hasConceptScore W2408255425C192209626 @default.
• W2408255425 hasConceptScore W2408255425C20556612 @default.
• W2408255425 hasConceptScore W2408255425C206041023 @default.
• W2408255425 hasConceptScore W2408255425C2776993930 @default.
• W2408255425 hasConceptScore W2408255425C33923547 @default.
• W2408255425 hasConceptScore W2408255425C62520636 @default.
• W2408255425 hasConceptScore W2408255425C65409693 @default.
• W2408255425 hasConceptScore W2408255425C71924100 @default.
• W2408255425 hasConceptScore W2408255425C87007009 @default.
• W2408255425 hasConceptScore W2408255425C96608239 @default.
• W2408255425 hasLocation W24082554251 @default.
• W2408255425 hasLocation W24082554252 @default.
• W2408255425 hasOpenAccess W2408255425 @default.
• W2408255425 hasPrimaryLocation W24082554251 @default.
• W2408255425 hasRelatedWork W174051407 @default.
• W2408255425 hasRelatedWork W2003109612 @default.
• W2408255425 hasRelatedWork W2015235728 @default.
• W2408255425 hasRelatedWork W2035183717 @default.
• W2408255425 hasRelatedWork W2036600297 @default.
• W2408255425 hasRelatedWork W2150426687 @default.
• W2408255425 hasRelatedWork W229910980 @default.
• W2408255425 hasRelatedWork W2621969506 @default.
• W2408255425 hasRelatedWork W2897830442 @default.
• W2408255425 hasRelatedWork W3007549562 @default.
• W2408255425 isParatext "false" @default.
• W2408255425 isRetracted "false" @default.
• W2408255425 magId "2408255425" @default.
• W2408255425 workType "article" @default.