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- W2408301085 abstract "Classical primary immunodeficiencies confer a predisposition to multiple microorganisms or recurrent infectious diseases. However, over the last 30 years, a molecular explanation has been proposed for the severe idiopathic infections caused by viruses, mycobacteria, pyogenic bacteria, or fungi, such as Candida, in particular. Defects of several biologically related genes may confer a selective predisposition to infections with one of these specific groups of pathogens in otherwise healthy individuals. Such individuals present a new type of primary immunodeficiency, with severe and/or recurrent infections caused by a single family of microorganisms, as opposed to the broader defects in patients with ‘classical’ primary immunodeficiencies." @default.
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- W2408301085 date "2016-01-01" @default.
- W2408301085 modified "2023-09-23" @default.
- W2408301085 title "Mendelian Susceptibility to Infections with Viruses, Mycobacteria, Bacteria, and Candida" @default.
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- W2408301085 doi "https://doi.org/10.1016/b978-0-12-374279-7.18021-x" @default.
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