Matches in SemOpenAlex for { <https://semopenalex.org/work/W2408314916> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2408314916 endingPage "11" @default.
- W2408314916 startingPage "203" @default.
- W2408314916 abstract "The aim of this study was to evaluate the correlation between NK (natural killers) cells in an inflammatory infiltration of the liver and in peripheral blood in children with chronic hepatitis type C.The study comprised 25 children with chronic hepatitis type C. The control group comprised 10 children with no liver disease in past medical history and normal activity of aminotransferases. In the study group, liver biopsy specimens were evaluated by histopathology and immunomorphology - the presence of NK cells present in the inflammatory infiltrate was determined. In all children the percentage and absolute count of NK cells in peripheral blood was evaluated by flow cytometry, as well as the activity of NK cells in relation to leukaemic cells of erythroleukemia K-562 without stimulation and after the stimulation with IL-2 (in vitro).In the studied group of children NK cells constituted 6.07 +/- 3.92 % of cells present in liver infiltrate. In peripheral blood NK cells constituted 11.68 +/- 6.73 % of white blood cells, and their absolute number was 241.08 +/- 128.56 /ml. The cytotoxic activity of NK cells in dilution E:T 25:1 was - 91.8 +/- 1.07 % and in dilution E:T 12.5:1 - 6.72 +/- 3.68 %. After stimulation with IL-2 it was 92.8 +/-1.01 % and 7.58 +/- 3.95 %, respectively. The number of NK cells in peripheral blood and cytotoxic activity of NK cells in the studied group did not differ from that of the control group. There was a positive correlation between the percentage of NK cells in the liver infiltrate and the absolute number of NK cells in the peripheral blood and between percentage of NK cells in the inflammatory infiltrate and cytotoxic activity of NK cells in peripheral blood, stimulated and non-stimulated with IL-2 in proportion E:T 12.5:1.Positive correlation between the number of NK cells in peripheral blood and liver infiltrate suggests the possibility of evaluating NK cells involvement in the pathogenesis of chronic hepatitis type C in children on the basis of peripheral blood tests." @default.
- W2408314916 created "2016-06-24" @default.
- W2408314916 creator A5004131774 @default.
- W2408314916 creator A5005000254 @default.
- W2408314916 creator A5028190477 @default.
- W2408314916 creator A5031227531 @default.
- W2408314916 creator A5053585229 @default.
- W2408314916 creator A5059165719 @default.
- W2408314916 date "2003-03-15" @default.
- W2408314916 modified "2023-10-18" @default.
- W2408314916 title "[Intrahepatic and peripheral blood NK cells in patients with chronic hepatitis C]." @default.
- W2408314916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12637774" @default.
- W2408314916 hasPublicationYear "2003" @default.
- W2408314916 type Work @default.
- W2408314916 sameAs 2408314916 @default.
- W2408314916 citedByCount "0" @default.
- W2408314916 crossrefType "journal-article" @default.
- W2408314916 hasAuthorship W2408314916A5004131774 @default.
- W2408314916 hasAuthorship W2408314916A5005000254 @default.
- W2408314916 hasAuthorship W2408314916A5028190477 @default.
- W2408314916 hasAuthorship W2408314916A5031227531 @default.
- W2408314916 hasAuthorship W2408314916A5053585229 @default.
- W2408314916 hasAuthorship W2408314916A5059165719 @default.
- W2408314916 hasConcept C126322002 @default.
- W2408314916 hasConcept C129374314 @default.
- W2408314916 hasConcept C142724271 @default.
- W2408314916 hasConcept C149532602 @default.
- W2408314916 hasConcept C154317977 @default.
- W2408314916 hasConcept C202751555 @default.
- W2408314916 hasConcept C203014093 @default.
- W2408314916 hasConcept C24998067 @default.
- W2408314916 hasConcept C2776029263 @default.
- W2408314916 hasConcept C2776090121 @default.
- W2408314916 hasConcept C553184892 @default.
- W2408314916 hasConcept C55493867 @default.
- W2408314916 hasConcept C71924100 @default.
- W2408314916 hasConcept C86803240 @default.
- W2408314916 hasConcept C8891405 @default.
- W2408314916 hasConceptScore W2408314916C126322002 @default.
- W2408314916 hasConceptScore W2408314916C129374314 @default.
- W2408314916 hasConceptScore W2408314916C142724271 @default.
- W2408314916 hasConceptScore W2408314916C149532602 @default.
- W2408314916 hasConceptScore W2408314916C154317977 @default.
- W2408314916 hasConceptScore W2408314916C202751555 @default.
- W2408314916 hasConceptScore W2408314916C203014093 @default.
- W2408314916 hasConceptScore W2408314916C24998067 @default.
- W2408314916 hasConceptScore W2408314916C2776029263 @default.
- W2408314916 hasConceptScore W2408314916C2776090121 @default.
- W2408314916 hasConceptScore W2408314916C553184892 @default.
- W2408314916 hasConceptScore W2408314916C55493867 @default.
- W2408314916 hasConceptScore W2408314916C71924100 @default.
- W2408314916 hasConceptScore W2408314916C86803240 @default.
- W2408314916 hasConceptScore W2408314916C8891405 @default.
- W2408314916 hasIssue "3" @default.
- W2408314916 hasLocation W24083149161 @default.
- W2408314916 hasOpenAccess W2408314916 @default.
- W2408314916 hasPrimaryLocation W24083149161 @default.
- W2408314916 hasRelatedWork W1560116787 @default.
- W2408314916 hasRelatedWork W2002809032 @default.
- W2408314916 hasRelatedWork W2049687639 @default.
- W2408314916 hasRelatedWork W2072502005 @default.
- W2408314916 hasRelatedWork W2074969559 @default.
- W2408314916 hasRelatedWork W2075860987 @default.
- W2408314916 hasRelatedWork W2103972237 @default.
- W2408314916 hasRelatedWork W2437787591 @default.
- W2408314916 hasRelatedWork W2797922834 @default.
- W2408314916 hasRelatedWork W2991630458 @default.
- W2408314916 hasVolume "6" @default.
- W2408314916 isParatext "false" @default.
- W2408314916 isRetracted "false" @default.
- W2408314916 magId "2408314916" @default.
- W2408314916 workType "article" @default.