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- W2408486596 abstract "miR-34a-mediated asymmetric cell division reins in excessive stem cell expansion during tissue regeneration in the intestine and colon. Loss of miR-34a switches asymmetric division to symmetric division and enhances stem cell proliferation. Asymmetric division also occurs in the early stages of colon cancer stem cells. Mechanistically, miR-34a, Numb, and Notch form a feed-forward loop that specifies cell fate when stem cells divide." @default.
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- W2408486596 date "2016-05-31" @default.
- W2408486596 modified "2023-09-25" @default.
- W2408486596 title "Asymmetric division: An antitumor player?" @default.
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- W2408486596 doi "https://doi.org/10.1080/23723556.2016.1164279" @default.
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