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• W2408548805 abstract "This article contributes to the development of an anthropology of biomedicine that takes as its subject matter the content of biomedical knowledge and practices. It offers an ethnographic account of the establishment of the international classification of white blood cells, known as the nomenclature, and goes beyond the assertion that biomedical knowledge is socially constructed, providing afine-textured analysis of how, in this specific case, knowledge was constituted. The CD nomenclature found its way into newspapers and daily medical practice mainly through the involvement of the CD4 subclass of lymphocytes (white blood cells) in AIDS definition and diagnosis. The establishment of the CD nomenclature is thus part of the recent movement of immunology to the center stage of the biomedical sciences. This study analyzes the articulation of the elements (institutions, tools, concepts) that made the classification possible. By focusing on the material practices of immunologists, the analysis shows that the present-day classification of lymphocytes has as its precondition the constitution of a network for the establishment of identities between immunological reagents produced by different laboratories. Furthermore, it is argued that the standards by which identities are established are inseparable from the entities (lymphocyte subsets) that are classified. Finally, it is claimed that an ethnography of the practices by which such a network comes into being provides an adequate analysis of the constitution of knowledge, specifically, of scientific information about the entities known as lymphocyte subsets. [immunology, lymphocytes, classification, anthropology of biomedical knowledge] In this article, we offer an ethnographic account of the proliferation of immunological entities known as T lymphocyte (or T cell) subsets, which have been recently implicated in the definition and diagnosis of diseases such as AIDS, leukemia, and autoimmune diseases, as well as in the monitoring of transplant patients. Thus, our study offers insights into the changing role and status of im" @default.
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• W2408548805 date "2016-01-01" @default.
• W2408548805 modified "2023-10-06" @default.
• W2408548805 title "Constituting Novel Entities in Immunology" @default.
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