Matches in SemOpenAlex for { <https://semopenalex.org/work/W2408647147> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2408647147 endingPage "90" @default.
- W2408647147 startingPage "86" @default.
- W2408647147 abstract "Neurofibromatosis type 1 (NF1) is a common inherited disorder with an autosomal dominant trait. We encountered an NF1 patient who showed adrenal pheochromocytoma, and analyzed expression of neurofibromin in an excised specimen. A 54-year-old man showing multiple neurofibromas and café-au-lait spots in the skin was pointed out to have a right adrenal tumor by ultrasonography. Abdominal CT also revealed a right adrenal tumor. He was diagnosed with neurofibromatosis type 1 with no family history. Urine catecholamines, metanephrine, and normetanephrine levels were elevated. MIBG scintigraphy showed positive right adrenal uptake, and so pheochromocytoma was also diagnosed. The patient underwent laparoscopic right adrenalectomy. The excised adrenal specimen of this patient was stained with anti-neurofibromin polyclonal antibody. The NF1 pheochromocytoma was completely negative for neurofibromin protein expression, while the NF1 non-pheochromocytomatous adrenal medulla was neurofibromin-positive in the cytoplasm and nucleus. The clear discrepancy in neurofibromin expression between pheochromocytoma cells and “normal” adrenal medullary cells of the patient may well be explained by Knudson’s two-hit hypothesis." @default.
- W2408647147 created "2016-06-24" @default.
- W2408647147 creator A5011360086 @default.
- W2408647147 creator A5018924780 @default.
- W2408647147 creator A5021072126 @default.
- W2408647147 creator A5035210412 @default.
- W2408647147 creator A5035937276 @default.
- W2408647147 creator A5038671423 @default.
- W2408647147 creator A5043328530 @default.
- W2408647147 creator A5091251773 @default.
- W2408647147 date "2016-01-01" @default.
- W2408647147 modified "2023-10-02" @default.
- W2408647147 title "Clear Discrepancy in Neurofibromin Expression between NF1 Pheochromocytoma Cells and Non-Tumorous Adrenal Medullary Cells" @default.
- W2408647147 cites W1574826837 @default.
- W2408647147 cites W1976956469 @default.
- W2408647147 cites W1978613276 @default.
- W2408647147 cites W1985305310 @default.
- W2408647147 cites W1990833369 @default.
- W2408647147 cites W1998114694 @default.
- W2408647147 cites W2017444651 @default.
- W2408647147 cites W2059196520 @default.
- W2408647147 cites W2074145013 @default.
- W2408647147 cites W2132188293 @default.
- W2408647147 cites W2132348205 @default.
- W2408647147 cites W2153292182 @default.
- W2408647147 cites W2161540890 @default.
- W2408647147 cites W2170137378 @default.
- W2408647147 cites W2321715789 @default.
- W2408647147 doi "https://doi.org/10.4236/oju.2016.65016" @default.
- W2408647147 hasPublicationYear "2016" @default.
- W2408647147 type Work @default.
- W2408647147 sameAs 2408647147 @default.
- W2408647147 citedByCount "0" @default.
- W2408647147 crossrefType "journal-article" @default.
- W2408647147 hasAuthorship W2408647147A5011360086 @default.
- W2408647147 hasAuthorship W2408647147A5018924780 @default.
- W2408647147 hasAuthorship W2408647147A5021072126 @default.
- W2408647147 hasAuthorship W2408647147A5035210412 @default.
- W2408647147 hasAuthorship W2408647147A5035937276 @default.
- W2408647147 hasAuthorship W2408647147A5038671423 @default.
- W2408647147 hasAuthorship W2408647147A5043328530 @default.
- W2408647147 hasAuthorship W2408647147A5091251773 @default.
- W2408647147 hasBestOaLocation W24086471471 @default.
- W2408647147 hasConcept C126322002 @default.
- W2408647147 hasConcept C134018914 @default.
- W2408647147 hasConcept C142724271 @default.
- W2408647147 hasConcept C170932241 @default.
- W2408647147 hasConcept C2778525890 @default.
- W2408647147 hasConcept C2778984943 @default.
- W2408647147 hasConcept C2779512018 @default.
- W2408647147 hasConcept C2780233176 @default.
- W2408647147 hasConcept C2780694816 @default.
- W2408647147 hasConcept C71924100 @default.
- W2408647147 hasConceptScore W2408647147C126322002 @default.
- W2408647147 hasConceptScore W2408647147C134018914 @default.
- W2408647147 hasConceptScore W2408647147C142724271 @default.
- W2408647147 hasConceptScore W2408647147C170932241 @default.
- W2408647147 hasConceptScore W2408647147C2778525890 @default.
- W2408647147 hasConceptScore W2408647147C2778984943 @default.
- W2408647147 hasConceptScore W2408647147C2779512018 @default.
- W2408647147 hasConceptScore W2408647147C2780233176 @default.
- W2408647147 hasConceptScore W2408647147C2780694816 @default.
- W2408647147 hasConceptScore W2408647147C71924100 @default.
- W2408647147 hasIssue "05" @default.
- W2408647147 hasLocation W24086471471 @default.
- W2408647147 hasOpenAccess W2408647147 @default.
- W2408647147 hasPrimaryLocation W24086471471 @default.
- W2408647147 hasRelatedWork W1970251377 @default.
- W2408647147 hasRelatedWork W1973661188 @default.
- W2408647147 hasRelatedWork W1979463295 @default.
- W2408647147 hasRelatedWork W1985305310 @default.
- W2408647147 hasRelatedWork W2037768492 @default.
- W2408647147 hasRelatedWork W2043121195 @default.
- W2408647147 hasRelatedWork W2074171531 @default.
- W2408647147 hasRelatedWork W2147779903 @default.
- W2408647147 hasRelatedWork W2408647147 @default.
- W2408647147 hasRelatedWork W4226321974 @default.
- W2408647147 hasVolume "06" @default.
- W2408647147 isParatext "false" @default.
- W2408647147 isRetracted "false" @default.
- W2408647147 magId "2408647147" @default.
- W2408647147 workType "article" @default.