Matches in SemOpenAlex for { <https://semopenalex.org/work/W2409017433> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2409017433 endingPage "515" @default.
- W2409017433 startingPage "507" @default.
- W2409017433 abstract "The HLA system is comprised of more than 30 class I and class II genes that encode a polymorphic array of cell-surface glycoprotein molecules that function to restrict or direct the specificity of T-cell responses. Class I alloantigens, encoded by HLA-A, -B, and -C genes, historically have been identified and characterized by the use of alloantisera. Three additional class I genes, HLA-E, -F, and -G, have been identified recently, but it is not known yet if these are relevant to transplantation. The demonstration of further polymorphism among class I alleles, however, has been made possible by the use of cytotoxic lymphocytes and by isoelectric focusing gel electrophoresis. Class II alloantigens, encoded by DR, DQ, and DP genes residing in the HLA-D region, can be defined both serologically and by the use of cellular reagents. Recent advances in DNA typing methods, including restriction fragment length polymorphism and sequence-specific oligonucleotide probe analysis, provide tools which more completely define the extent of HLA polymorphism within given populations. The diversity of allelic variation within the HLA system, coupled with the fundamental role of class I and class II molecules in the triggering of allograft reactions, necessitates the continuing improvement of techniques for characterizing distinct HLA molecules and providing for the better matching of donor and recipient prior to allotransplantation." @default.
- W2409017433 created "2016-06-24" @default.
- W2409017433 creator A5027765321 @default.
- W2409017433 creator A5030600192 @default.
- W2409017433 creator A5030733029 @default.
- W2409017433 creator A5031845415 @default.
- W2409017433 date "1990-06-01" @default.
- W2409017433 modified "2023-10-18" @default.
- W2409017433 title "The HLA System in Clinical Marrow Transplantation" @default.
- W2409017433 cites W1685831503 @default.
- W2409017433 cites W1975418617 @default.
- W2409017433 cites W1991982391 @default.
- W2409017433 cites W1993483977 @default.
- W2409017433 cites W2009628982 @default.
- W2409017433 cites W2046788012 @default.
- W2409017433 cites W2056927502 @default.
- W2409017433 cites W2059480152 @default.
- W2409017433 cites W2069066407 @default.
- W2409017433 cites W2079121383 @default.
- W2409017433 cites W2111441225 @default.
- W2409017433 cites W2143608149 @default.
- W2409017433 cites W2153085701 @default.
- W2409017433 cites W2155784158 @default.
- W2409017433 doi "https://doi.org/10.1016/s0889-8588(18)30475-1" @default.
- W2409017433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2193011" @default.
- W2409017433 hasPublicationYear "1990" @default.
- W2409017433 type Work @default.
- W2409017433 sameAs 2409017433 @default.
- W2409017433 citedByCount "12" @default.
- W2409017433 countsByYear W24090174332014 @default.
- W2409017433 crossrefType "journal-article" @default.
- W2409017433 hasAuthorship W2409017433A5027765321 @default.
- W2409017433 hasAuthorship W2409017433A5030600192 @default.
- W2409017433 hasAuthorship W2409017433A5030733029 @default.
- W2409017433 hasAuthorship W2409017433A5031845415 @default.
- W2409017433 hasConcept C104317684 @default.
- W2409017433 hasConcept C135763542 @default.
- W2409017433 hasConcept C141071460 @default.
- W2409017433 hasConcept C147483822 @default.
- W2409017433 hasConcept C153911025 @default.
- W2409017433 hasConcept C168007829 @default.
- W2409017433 hasConcept C180754005 @default.
- W2409017433 hasConcept C188280979 @default.
- W2409017433 hasConcept C2777561873 @default.
- W2409017433 hasConcept C2781209916 @default.
- W2409017433 hasConcept C2911091166 @default.
- W2409017433 hasConcept C31467283 @default.
- W2409017433 hasConcept C49105822 @default.
- W2409017433 hasConcept C54355233 @default.
- W2409017433 hasConcept C70721500 @default.
- W2409017433 hasConcept C71924100 @default.
- W2409017433 hasConcept C86803240 @default.
- W2409017433 hasConceptScore W2409017433C104317684 @default.
- W2409017433 hasConceptScore W2409017433C135763542 @default.
- W2409017433 hasConceptScore W2409017433C141071460 @default.
- W2409017433 hasConceptScore W2409017433C147483822 @default.
- W2409017433 hasConceptScore W2409017433C153911025 @default.
- W2409017433 hasConceptScore W2409017433C168007829 @default.
- W2409017433 hasConceptScore W2409017433C180754005 @default.
- W2409017433 hasConceptScore W2409017433C188280979 @default.
- W2409017433 hasConceptScore W2409017433C2777561873 @default.
- W2409017433 hasConceptScore W2409017433C2781209916 @default.
- W2409017433 hasConceptScore W2409017433C2911091166 @default.
- W2409017433 hasConceptScore W2409017433C31467283 @default.
- W2409017433 hasConceptScore W2409017433C49105822 @default.
- W2409017433 hasConceptScore W2409017433C54355233 @default.
- W2409017433 hasConceptScore W2409017433C70721500 @default.
- W2409017433 hasConceptScore W2409017433C71924100 @default.
- W2409017433 hasConceptScore W2409017433C86803240 @default.
- W2409017433 hasIssue "3" @default.
- W2409017433 hasLocation W24090174331 @default.
- W2409017433 hasLocation W24090174332 @default.
- W2409017433 hasOpenAccess W2409017433 @default.
- W2409017433 hasPrimaryLocation W24090174331 @default.
- W2409017433 hasRelatedWork W121700474 @default.
- W2409017433 hasRelatedWork W2010208430 @default.
- W2409017433 hasRelatedWork W2057739827 @default.
- W2409017433 hasRelatedWork W2356600424 @default.
- W2409017433 hasRelatedWork W2416344185 @default.
- W2409017433 hasRelatedWork W2563618055 @default.
- W2409017433 hasRelatedWork W2591382458 @default.
- W2409017433 hasRelatedWork W2807106904 @default.
- W2409017433 hasRelatedWork W3032525565 @default.
- W2409017433 hasRelatedWork W182926708 @default.
- W2409017433 hasVolume "4" @default.
- W2409017433 isParatext "false" @default.
- W2409017433 isRetracted "false" @default.
- W2409017433 magId "2409017433" @default.
- W2409017433 workType "article" @default.