Matches in SemOpenAlex for { <https://semopenalex.org/work/W2409257413> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2409257413 endingPage "32" @default.
- W2409257413 startingPage "126" @default.
- W2409257413 abstract "Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous extract of caper (Capparis spinosa) buds on lipopolysaccharide-induced cognitive impairment in rats using two different oral doses i.e. 10 (pre-treatment) and 30 mg/rat(post-treatment) through assessment of behavioural (Morris Water maze test and Y maze test), biochemical (Cholinesterase assay) and histopathological (H&E staining) parameters. Lipopolysaccharide (from E. coli) administration resulted in an increased neurodegeneration and time taken to reach the platform (in Morris water maze). The increased neurodegeneration in CA1 region of hippocampus was significantly reduced in animals which received caper bud extract; they showed marked reduction in time taken to reach the platform at both the dose levels. The experiment demonstrated that caper bud extract exhibits potential protective effect against learning and memory damage induced by chronic administration of lipopolysaccharide (175 μg/kg) for 7 days. The results suggest that the caper bud extract could be explored for its use in the treatment of cognitive disorders." @default.
- W2409257413 created "2016-06-24" @default.
- W2409257413 creator A5017792039 @default.
- W2409257413 creator A5063055723 @default.
- W2409257413 creator A5065310453 @default.
- W2409257413 creator A5082237486 @default.
- W2409257413 date "2016-02-01" @default.
- W2409257413 modified "2023-09-26" @default.
- W2409257413 title "Effect of Capparis spinosa Linn. extract on lipopolysaccharide-induced cognitive impairment in rats." @default.
- W2409257413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26934780" @default.
- W2409257413 hasPublicationYear "2016" @default.
- W2409257413 type Work @default.
- W2409257413 sameAs 2409257413 @default.
- W2409257413 citedByCount "5" @default.
- W2409257413 countsByYear W24092574132017 @default.
- W2409257413 countsByYear W24092574132018 @default.
- W2409257413 countsByYear W24092574132020 @default.
- W2409257413 countsByYear W24092574132022 @default.
- W2409257413 countsByYear W24092574132023 @default.
- W2409257413 crossrefType "journal-article" @default.
- W2409257413 hasAuthorship W2409257413A5017792039 @default.
- W2409257413 hasAuthorship W2409257413A5063055723 @default.
- W2409257413 hasAuthorship W2409257413A5065310453 @default.
- W2409257413 hasAuthorship W2409257413A5082237486 @default.
- W2409257413 hasConcept C118552586 @default.
- W2409257413 hasConcept C126322002 @default.
- W2409257413 hasConcept C169900460 @default.
- W2409257413 hasConcept C2776925932 @default.
- W2409257413 hasConcept C2778754761 @default.
- W2409257413 hasConcept C2779134260 @default.
- W2409257413 hasConcept C2780749935 @default.
- W2409257413 hasConcept C2781161787 @default.
- W2409257413 hasConcept C2909605514 @default.
- W2409257413 hasConcept C2984915365 @default.
- W2409257413 hasConcept C44752575 @default.
- W2409257413 hasConcept C556039675 @default.
- W2409257413 hasConcept C71924100 @default.
- W2409257413 hasConcept C98274493 @default.
- W2409257413 hasConceptScore W2409257413C118552586 @default.
- W2409257413 hasConceptScore W2409257413C126322002 @default.
- W2409257413 hasConceptScore W2409257413C169900460 @default.
- W2409257413 hasConceptScore W2409257413C2776925932 @default.
- W2409257413 hasConceptScore W2409257413C2778754761 @default.
- W2409257413 hasConceptScore W2409257413C2779134260 @default.
- W2409257413 hasConceptScore W2409257413C2780749935 @default.
- W2409257413 hasConceptScore W2409257413C2781161787 @default.
- W2409257413 hasConceptScore W2409257413C2909605514 @default.
- W2409257413 hasConceptScore W2409257413C2984915365 @default.
- W2409257413 hasConceptScore W2409257413C44752575 @default.
- W2409257413 hasConceptScore W2409257413C556039675 @default.
- W2409257413 hasConceptScore W2409257413C71924100 @default.
- W2409257413 hasConceptScore W2409257413C98274493 @default.
- W2409257413 hasIssue "2" @default.
- W2409257413 hasLocation W24092574131 @default.
- W2409257413 hasOpenAccess W2409257413 @default.
- W2409257413 hasPrimaryLocation W24092574131 @default.
- W2409257413 hasRelatedWork W1980645669 @default.
- W2409257413 hasRelatedWork W2011693499 @default.
- W2409257413 hasRelatedWork W2069906799 @default.
- W2409257413 hasRelatedWork W2070533987 @default.
- W2409257413 hasRelatedWork W2167928402 @default.
- W2409257413 hasRelatedWork W2352523093 @default.
- W2409257413 hasRelatedWork W2523039730 @default.
- W2409257413 hasRelatedWork W3045101120 @default.
- W2409257413 hasRelatedWork W4293659716 @default.
- W2409257413 hasRelatedWork W82234544 @default.
- W2409257413 hasVolume "54" @default.
- W2409257413 isParatext "false" @default.
- W2409257413 isRetracted "false" @default.
- W2409257413 magId "2409257413" @default.
- W2409257413 workType "article" @default.