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- W2409357816 abstract "A possible direct renal effect of thyroid hormone was investigated by administering 1.0 mg 3,5,3' l-triiodothyronine (T 3 ) to normal dogs, and measuring the excretion of calcium, phosphorus, magnesium, creatinine and nitrogen for 4 1/2 hours thereafter. In contrast to controls, a pronounced rise in urinary phosphorus regularly followed T 3 . Renal clearance of phosphorus increased, and tubular reabsorption fell to a mean of 68% of the filtered phosphorus load. A similar response occurred in dogs without parathyroid glands. No increase in calcium, magnesium or nitrogen excretion accompanied the acute phosphaturesis. These results indicate a direct action of triiodothyronine on the renal tubule independent of the level of parathyroid activity." @default.
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- W2409357816 date "1958-10-31" @default.
- W2409357816 modified "2023-09-26" @default.
- W2409357816 title "Phosphaturesis: a Direct Renal Effect of Triiodothyronine" @default.
- W2409357816 doi "https://doi.org/10.1152/ajplegacy.1958.195.2.357" @default.
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