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- W2409453722 abstract "Cyclin-dependent kinases have established roles in the regulation of cell cycle, in gene expression and in cell differentiation. Many of these kinases have been considered as drug targets and numerous efforts have been made to develop specific and potent inhibitors against them. The first step in all of these attempts and in many other biochemical analyses is the production of highly purified and reliable kinase, most frequently in a recombinant form. In this chapter we describe our experience in the cloning, expression, and purification of CDKs using CDK7/CycH, CDK8/CycC, and CDK9/CycT1 as an example." @default.
- W2409453722 created "2016-06-24" @default.
- W2409453722 creator A5044004802 @default.
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- W2409453722 date "2016-01-01" @default.
- W2409453722 modified "2023-09-23" @default.
- W2409453722 title "Expression and Purification of Recombinant CDKs: CDK7, CDK8, and CDK9" @default.
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- W2409453722 doi "https://doi.org/10.1007/978-1-4939-2926-9_3" @default.
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