Matches in SemOpenAlex for { <https://semopenalex.org/work/W2409626979> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2409626979 endingPage "C115" @default.
- W2409626979 startingPage "C110" @default.
- W2409626979 abstract "Prolactin is a known osmoregulatory hormone in lower vertebrates, and recent evidence indicates that this hormone modulates ionic concentrations in milk. In an ultrastructurally and biochemically differentiated primary cell culture system in which mouse mammary epithelium is maintained on floating collagen gels, prolactin causes an increase in short-circuit current (Isc) of monolayers of cells derived from midpregnant (24.6 to 48.0 microA . cm-2) and lactating (10.4 to 16.1 microA . cm-2) glands. Transepithelial potential differences (basal side ground) average about -12 mV and are similar to those seen in vivo. Prelactating mammary epithelial cell cultures have transepithelial resistances ranging from 374 omega . cm2 (prolactin present) to 507 omega . cm2 (prolactin absent), and lactating cell cultures have resistances averaging almost 1,000 omega . cm2. Prolactin effects require at most one day of culture maintenance in prolactin-containing medium, and the effects are not due to known contamination of prolactin preparations with arginine vasopressin or growth hormone. Medium concentrations of prolactin as low as 1 ng/ml can elicit these effects. In prelactating cell cultures not treated with prolactin, the Isc is equal to the rate of sodium absorption. Prolactin increases sodium absorption fourfold but increases Isc only twofold. Clearly, prolactin induces other active transport; neither potassium nor chloride movements can account for this additional transport. Resistance values, current-voltage plots, and permeability coefficients indicate that in vitro mammary epithelium is a moderately “tight” tissue. Comparisons with intact glands indicate that in vitro mammary epithelium closely resembles its in vivo counterpart. Floating collagen gel cultures appear suitable for elucidating transport properties in cellularly heterogeneous and structurally complex mammalian tissues." @default.
- W2409626979 created "2016-06-24" @default.
- W2409626979 creator A5020660126 @default.
- W2409626979 date "1981-03-01" @default.
- W2409626979 modified "2023-09-23" @default.
- W2409626979 title "Prolactin effects on ion transport across cultured mouse mammary epithelium" @default.
- W2409626979 cites W1565526431 @default.
- W2409626979 cites W1978351404 @default.
- W2409626979 cites W1991279507 @default.
- W2409626979 cites W2003003393 @default.
- W2409626979 cites W2005431113 @default.
- W2409626979 cites W2010486279 @default.
- W2409626979 cites W2025050741 @default.
- W2409626979 cites W2030485204 @default.
- W2409626979 cites W2034585819 @default.
- W2409626979 cites W2041170371 @default.
- W2409626979 cites W2042584846 @default.
- W2409626979 cites W2045084108 @default.
- W2409626979 cites W2045959446 @default.
- W2409626979 cites W2051234204 @default.
- W2409626979 cites W2051372939 @default.
- W2409626979 cites W2073862596 @default.
- W2409626979 cites W2076052456 @default.
- W2409626979 cites W2076590661 @default.
- W2409626979 cites W2089446876 @default.
- W2409626979 cites W2128001486 @default.
- W2409626979 cites W2157264568 @default.
- W2409626979 cites W2408233095 @default.
- W2409626979 cites W2418595983 @default.
- W2409626979 doi "https://doi.org/10.1152/ajpcell.1981.240.3.c110" @default.
- W2409626979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7011046" @default.
- W2409626979 hasPublicationYear "1981" @default.
- W2409626979 type Work @default.
- W2409626979 sameAs 2409626979 @default.
- W2409626979 citedByCount "26" @default.
- W2409626979 countsByYear W24096269792014 @default.
- W2409626979 countsByYear W24096269792018 @default.
- W2409626979 crossrefType "journal-article" @default.
- W2409626979 hasAuthorship W2409626979A5020660126 @default.
- W2409626979 hasConcept C126322002 @default.
- W2409626979 hasConcept C134018914 @default.
- W2409626979 hasConcept C150903083 @default.
- W2409626979 hasConcept C185592680 @default.
- W2409626979 hasConcept C207001950 @default.
- W2409626979 hasConcept C2776370428 @default.
- W2409626979 hasConcept C2779064019 @default.
- W2409626979 hasConcept C28938303 @default.
- W2409626979 hasConcept C41625074 @default.
- W2409626979 hasConcept C529295009 @default.
- W2409626979 hasConcept C54355233 @default.
- W2409626979 hasConcept C54799321 @default.
- W2409626979 hasConcept C55493867 @default.
- W2409626979 hasConcept C71315377 @default.
- W2409626979 hasConcept C71924100 @default.
- W2409626979 hasConcept C86803240 @default.
- W2409626979 hasConcept C99975950 @default.
- W2409626979 hasConceptScore W2409626979C126322002 @default.
- W2409626979 hasConceptScore W2409626979C134018914 @default.
- W2409626979 hasConceptScore W2409626979C150903083 @default.
- W2409626979 hasConceptScore W2409626979C185592680 @default.
- W2409626979 hasConceptScore W2409626979C207001950 @default.
- W2409626979 hasConceptScore W2409626979C2776370428 @default.
- W2409626979 hasConceptScore W2409626979C2779064019 @default.
- W2409626979 hasConceptScore W2409626979C28938303 @default.
- W2409626979 hasConceptScore W2409626979C41625074 @default.
- W2409626979 hasConceptScore W2409626979C529295009 @default.
- W2409626979 hasConceptScore W2409626979C54355233 @default.
- W2409626979 hasConceptScore W2409626979C54799321 @default.
- W2409626979 hasConceptScore W2409626979C55493867 @default.
- W2409626979 hasConceptScore W2409626979C71315377 @default.
- W2409626979 hasConceptScore W2409626979C71924100 @default.
- W2409626979 hasConceptScore W2409626979C86803240 @default.
- W2409626979 hasConceptScore W2409626979C99975950 @default.
- W2409626979 hasIssue "3" @default.
- W2409626979 hasLocation W24096269791 @default.
- W2409626979 hasLocation W24096269792 @default.
- W2409626979 hasOpenAccess W2409626979 @default.
- W2409626979 hasPrimaryLocation W24096269791 @default.
- W2409626979 hasRelatedWork W1973992041 @default.
- W2409626979 hasRelatedWork W2027947571 @default.
- W2409626979 hasRelatedWork W2031866754 @default.
- W2409626979 hasRelatedWork W2032920953 @default.
- W2409626979 hasRelatedWork W2048446494 @default.
- W2409626979 hasRelatedWork W2077944812 @default.
- W2409626979 hasRelatedWork W2094766549 @default.
- W2409626979 hasRelatedWork W2099444108 @default.
- W2409626979 hasRelatedWork W2152306407 @default.
- W2409626979 hasRelatedWork W2409626979 @default.
- W2409626979 hasVolume "240" @default.
- W2409626979 isParatext "false" @default.
- W2409626979 isRetracted "false" @default.
- W2409626979 magId "2409626979" @default.
- W2409626979 workType "article" @default.