Matches in SemOpenAlex for { <https://semopenalex.org/work/W2409726060> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2409726060 endingPage "80" @default.
- W2409726060 startingPage "278" @default.
- W2409726060 abstract "To establish an implanted model of human colonic carcinoma on chick embryo, and to study the effects of anti-angiopoietin-2 antibody on its vascularization.The human colonic adenocarcinoma cell line HT-29 was transplanted on the chick embryo's chorioallantoic membrane(CAM), and the angiogenesis characteristics were observed by stero-microscope, light microscope and immunohistochemistry. Furthermore, the effects of anti-angiopoietin-2 antibody on angiogenesis and tumor growth were also investigated.Three to seven days after HT-29 cell line was implanted into CAM, tumors grew rapidly and new blood vessels grew toward tumors. Five days after anti-angiopoietin-2 antibody was given, the number of blood vessels in anti-angiopoietin-2 antibody group was significantly down-regulated than that in tumor control group observed by stero-microscope (37.2+/-4.6 vs 56.8+/-7.4, P<0.01), but was up-regulated than that in normal control group (37.2+/-4.6 vs 9.6+/-2.4, P<0.01). Microvessel density(MVD) in anti-angiopoietin-2 antibody group was much lower than that in tumor control group by histological examination (9.6+/-2.4 vs 20.2+/-5.8, P<0.01).Angiopoietin-2 antibody is able to inhibit the angiogenesis induced by colorectal cancer cell line HT-29 obviously. The anti-angiopoietin-2 antibody may be potentially useful for clinical treatment of colonic carcinoma." @default.
- W2409726060 created "2016-06-24" @default.
- W2409726060 creator A5008723753 @default.
- W2409726060 creator A5061520207 @default.
- W2409726060 creator A5073046343 @default.
- W2409726060 creator A5088795755 @default.
- W2409726060 date "2007-05-01" @default.
- W2409726060 modified "2023-10-18" @default.
- W2409726060 title "[Effects of anti-angiopoietin-2 antibody on vascularization of an implanted model of human colonic carcinoma on chick embryo]." @default.
- W2409726060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17520390" @default.
- W2409726060 hasPublicationYear "2007" @default.
- W2409726060 type Work @default.
- W2409726060 sameAs 2409726060 @default.
- W2409726060 citedByCount "1" @default.
- W2409726060 crossrefType "journal-article" @default.
- W2409726060 hasAuthorship W2409726060A5008723753 @default.
- W2409726060 hasAuthorship W2409726060A5061520207 @default.
- W2409726060 hasAuthorship W2409726060A5073046343 @default.
- W2409726060 hasAuthorship W2409726060A5088795755 @default.
- W2409726060 hasConcept C121608353 @default.
- W2409726060 hasConcept C126322002 @default.
- W2409726060 hasConcept C142724271 @default.
- W2409726060 hasConcept C159654299 @default.
- W2409726060 hasConcept C167734588 @default.
- W2409726060 hasConcept C196843134 @default.
- W2409726060 hasConcept C203014093 @default.
- W2409726060 hasConcept C204232928 @default.
- W2409726060 hasConcept C2776436680 @default.
- W2409726060 hasConcept C2777025900 @default.
- W2409726060 hasConcept C2777546739 @default.
- W2409726060 hasConcept C2778271429 @default.
- W2409726060 hasConcept C2779094623 @default.
- W2409726060 hasConcept C2780394083 @default.
- W2409726060 hasConcept C2781182431 @default.
- W2409726060 hasConcept C2911142149 @default.
- W2409726060 hasConcept C502942594 @default.
- W2409726060 hasConcept C71924100 @default.
- W2409726060 hasConcept C85219853 @default.
- W2409726060 hasConcept C86803240 @default.
- W2409726060 hasConcept C95444343 @default.
- W2409726060 hasConcept C97230052 @default.
- W2409726060 hasConceptScore W2409726060C121608353 @default.
- W2409726060 hasConceptScore W2409726060C126322002 @default.
- W2409726060 hasConceptScore W2409726060C142724271 @default.
- W2409726060 hasConceptScore W2409726060C159654299 @default.
- W2409726060 hasConceptScore W2409726060C167734588 @default.
- W2409726060 hasConceptScore W2409726060C196843134 @default.
- W2409726060 hasConceptScore W2409726060C203014093 @default.
- W2409726060 hasConceptScore W2409726060C204232928 @default.
- W2409726060 hasConceptScore W2409726060C2776436680 @default.
- W2409726060 hasConceptScore W2409726060C2777025900 @default.
- W2409726060 hasConceptScore W2409726060C2777546739 @default.
- W2409726060 hasConceptScore W2409726060C2778271429 @default.
- W2409726060 hasConceptScore W2409726060C2779094623 @default.
- W2409726060 hasConceptScore W2409726060C2780394083 @default.
- W2409726060 hasConceptScore W2409726060C2781182431 @default.
- W2409726060 hasConceptScore W2409726060C2911142149 @default.
- W2409726060 hasConceptScore W2409726060C502942594 @default.
- W2409726060 hasConceptScore W2409726060C71924100 @default.
- W2409726060 hasConceptScore W2409726060C85219853 @default.
- W2409726060 hasConceptScore W2409726060C86803240 @default.
- W2409726060 hasConceptScore W2409726060C95444343 @default.
- W2409726060 hasConceptScore W2409726060C97230052 @default.
- W2409726060 hasIssue "3" @default.
- W2409726060 hasLocation W24097260601 @default.
- W2409726060 hasOpenAccess W2409726060 @default.
- W2409726060 hasPrimaryLocation W24097260601 @default.
- W2409726060 hasRelatedWork W1973599157 @default.
- W2409726060 hasRelatedWork W2078674849 @default.
- W2409726060 hasRelatedWork W2085052037 @default.
- W2409726060 hasRelatedWork W2113920157 @default.
- W2409726060 hasRelatedWork W2148883897 @default.
- W2409726060 hasRelatedWork W2171027850 @default.
- W2409726060 hasRelatedWork W2219451458 @default.
- W2409726060 hasRelatedWork W2361544672 @default.
- W2409726060 hasRelatedWork W2390281412 @default.
- W2409726060 hasRelatedWork W2409726060 @default.
- W2409726060 hasVolume "10" @default.
- W2409726060 isParatext "false" @default.
- W2409726060 isRetracted "false" @default.
- W2409726060 magId "2409726060" @default.
- W2409726060 workType "article" @default.