FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2409777908> ?p ?o ?g. }

• W2409777908 endingPage "115" @default.
• W2409777908 startingPage "107" @default.
• W2409777908 abstract "Glucocorticoid therapy is used widely in patients with rheumatoid arthritis (RA) with good efficacy but concerns about safety including fractures. Estimates of fracture risk for any given patient are complicated by the dynamic pattern of glucocorticoid use, where patients vary in their dose, duration and timing of glucocorticoid use. To investigate which methods are currently used to attribute fractures to glucocorticoid exposure and investigate whether such methods can consider individual treatment patterns. Thirty-eight studies used five common definitions of risk attribution to glucocorticoid exposure: “current use”, “ever use”, “daily dose”, “cumulative dose” and “time variant”. One study attempted to combine multiple definitions where “cumulative dose” was nested within “daily dose”, covering the effects of dose and duration but not timing. The majority of results demonstrated an equivocal or increased risk of fracture with increased exposure, although there was wide variation, with odds ratios, hazard ratios and relative risks ranging from 0.16 to 8.16. Within definitions there was also variability in the results with the smallest range for “time variant”, 1.07 to 2.8, and the largest for “cumulative dose”, ranging from risk estimates of 0.88 to 8.12. Many studies have looked into the effect of glucocorticoids on fracture risk in patients with RA. Despite this, there is no clear consensus about the magnitude of risk. This is a consequence of the varied analysis models and their different assumptions. Moreover, no current analysis method allows consideration of dose, duration and timing of glucocorticoid therapy, preventing a clear understanding of fracture risk for patients and their individual treatment patterns." @default.
• W2409777908 created "2016-06-24" @default.
• W2409777908 creator A5010969398 @default.
• W2409777908 creator A5016347038 @default.
• W2409777908 creator A5068193213 @default.
• W2409777908 creator A5075860605 @default.
• W2409777908 creator A5086010333 @default.
• W2409777908 date "2016-09-01" @default.
• W2409777908 modified "2023-10-06" @default.
• W2409777908 title "A review of the methods used to define glucocorticoid exposure and risk attribution when investigating the risk of fracture in a rheumatoid arthritis population" @default.
• W2409777908 cites W1953534612 @default.
• W2409777908 cites W1970654520 @default.
• W2409777908 cites W1976420337 @default.
• W2409777908 cites W1985324052 @default.
• W2409777908 cites W1985518172 @default.
• W2409777908 cites W1989553857 @default.
• W2409777908 cites W1994443194 @default.
• W2409777908 cites W2005432197 @default.
• W2409777908 cites W2007650860 @default.
• W2409777908 cites W2014927306 @default.
• W2409777908 cites W2040381233 @default.
• W2409777908 cites W2044598614 @default.
• W2409777908 cites W2047008569 @default.
• W2409777908 cites W2049335637 @default.
• W2409777908 cites W2053083658 @default.
• W2409777908 cites W2055697100 @default.
• W2409777908 cites W2057764823 @default.
• W2409777908 cites W2057907407 @default.
• W2409777908 cites W2060926765 @default.
• W2409777908 cites W2066641134 @default.
• W2409777908 cites W2069670824 @default.
• W2409777908 cites W2077468008 @default.
• W2409777908 cites W2080749768 @default.
• W2409777908 cites W2092395516 @default.
• W2409777908 cites W2093830944 @default.
• W2409777908 cites W2098986981 @default.
• W2409777908 cites W2108455224 @default.
• W2409777908 cites W2116937948 @default.
• W2409777908 cites W2123893299 @default.
• W2409777908 cites W2125645910 @default.
• W2409777908 cites W2128534784 @default.
• W2409777908 cites W2136478247 @default.
• W2409777908 cites W2142865003 @default.
• W2409777908 cites W2145539024 @default.
• W2409777908 cites W2149910975 @default.
• W2409777908 cites W2151991291 @default.
• W2409777908 cites W2156578916 @default.
• W2409777908 cites W2162068878 @default.
• W2409777908 cites W2169198657 @default.
• W2409777908 cites W4252764202 @default.
• W2409777908 cites W4255533032 @default.
• W2409777908 doi "https://doi.org/10.1016/j.bone.2016.06.001" @default.
• W2409777908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4973893" @default.
• W2409777908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27268854" @default.
• W2409777908 hasPublicationYear "2016" @default.
• W2409777908 type Work @default.
• W2409777908 sameAs 2409777908 @default.
• W2409777908 citedByCount "11" @default.
• W2409777908 countsByYear W24097779082017 @default.
• W2409777908 countsByYear W24097779082018 @default.
• W2409777908 countsByYear W24097779082019 @default.
• W2409777908 countsByYear W24097779082020 @default.
• W2409777908 countsByYear W24097779082021 @default.
• W2409777908 countsByYear W24097779082022 @default.
• W2409777908 crossrefType "journal-article" @default.
• W2409777908 hasAuthorship W2409777908A5010969398 @default.
• W2409777908 hasAuthorship W2409777908A5016347038 @default.
• W2409777908 hasAuthorship W2409777908A5068193213 @default.
• W2409777908 hasAuthorship W2409777908A5075860605 @default.
• W2409777908 hasAuthorship W2409777908A5086010333 @default.
• W2409777908 hasBestOaLocation W24097779081 @default.
• W2409777908 hasConcept C126322002 @default.
• W2409777908 hasConcept C151032500 @default.
• W2409777908 hasConcept C2777575956 @default.
• W2409777908 hasConcept C2780841215 @default.
• W2409777908 hasConcept C2908647359 @default.
• W2409777908 hasConcept C71924100 @default.
• W2409777908 hasConcept C99454951 @default.
• W2409777908 hasConceptScore W2409777908C126322002 @default.
• W2409777908 hasConceptScore W2409777908C151032500 @default.
• W2409777908 hasConceptScore W2409777908C2777575956 @default.
• W2409777908 hasConceptScore W2409777908C2780841215 @default.
• W2409777908 hasConceptScore W2409777908C2908647359 @default.
• W2409777908 hasConceptScore W2409777908C71924100 @default.
• W2409777908 hasConceptScore W2409777908C99454951 @default.
• W2409777908 hasFunder F4320320045 @default.
• W2409777908 hasLocation W24097779081 @default.
• W2409777908 hasLocation W24097779082 @default.
• W2409777908 hasLocation W24097779083 @default.
• W2409777908 hasLocation W24097779084 @default.
• W2409777908 hasLocation W24097779085 @default.
• W2409777908 hasOpenAccess W2409777908 @default.
• W2409777908 hasPrimaryLocation W24097779081 @default.
• W2409777908 hasRelatedWork W2041279917 @default.
• W2409777908 hasRelatedWork W2082406232 @default.
• W2409777908 hasRelatedWork W2156283049 @default.
• W2409777908 hasRelatedWork W2316954211 @default.
• W2409777908 hasRelatedWork W2326094713 @default.

• next