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- W2409970688 abstract "IMMUNOLOGICAL PARAMETER FOR CANCER PATIENTS: In this paper, we are the first to demonstrate that a disturbed immune system, especially imbalance between monocytes and T cells in peripheral blood mononuclear cells, is closely related to cancer recurrence. We have developed a parameter of immunocompetence in cancer patients, which we designated the monocyte/T cell(M/T) ratio. The M/T ratio was shown to be related to cytotoxic T lymphocyte activity in vitro. Furthermore, the M/T ratio should be useful for earlier detection of recurrence than conventional tumor markers. Early detection of recurrence would permit a timely retreatment decision and contribute to prolonged survival in cancer patients. IMMUNOLOGICAL EFFECTS OF KAMPO MEDICINE: Juzen-taiho-to (TJ-48) is a traditional kampo medicine used in Japan and China. We demonstrated in this paper that CD3+8+ cytotoxic T lymphocytes specific for autologous and HLA shared allogeneic tumor cells were induced from peripheral blood mononuclear cells stimulated by TJ-48 in vitro. Furthermore, we also demonstrated that the M/T ratio is decreased by administration of TJ-48 in patients with gynecologic cancer." @default.
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- W2409970688 date "2004-05-01" @default.
- W2409970688 modified "2023-09-25" @default.
- W2409970688 title "Kampo medicine and new immunological parameter" @default.
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