Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410003069> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2410003069 endingPage "7" @default.
- W2410003069 startingPage "451" @default.
- W2410003069 abstract "The clearance rate of inhaled aerosols of a lipophilic substance, 99mTc-HMPAO (Hexamethyl propylene amine oxime) was studied and compared to that of hydrophilic substances in 6 normal volunteers and 18 patients with lung diseases. The subject in sitting position inhaled a single deep breath of 99mTc-HMPAO aerosols, and held his breath about 30 sec. Then he continued to breath aerosols again for about 3 min. Radioactivity rapidly falls down during breath holding, to about 60% of the peak value (fast phase), with T 1/2 of 3.75 +/- 2.22 sec in 6 normal volunteers. This rapid phase was not appeared in hydrophilic aerosols with 99mTc-DTPA and 99mTc-pertechnetate and in lipophilic aerosol with 123I-IMP aerosol. The clearance of residual activity of 99mTc-HMPAO was slow with T 1/2 of 17.4 +/- 4.0 min. The T 1/2 of 99mTc-DTPA, 99mTc-pertechnetate and 123I-IMP were 50.2 +/- 20.9 min, 11.4 +/- 4.3, and 62.5 +/- 20.8 min respectively. 99mTc-HMPAO may cross transcellularly using the whole alveolar surface. The clearance of aerosols in the fast phase is rapid and depend on the regional perfusion. On the other hand, hydrophilic aerosol pass by an intercellular pathway and the clearance will be diffusion limited. As conclusion, inhalation study of 99mTc-HMPAO might be a new method to evaluate perfusion following ventilation study." @default.
- W2410003069 created "2016-06-24" @default.
- W2410003069 creator A5008250803 @default.
- W2410003069 creator A5033106552 @default.
- W2410003069 creator A5036610255 @default.
- W2410003069 creator A5050788544 @default.
- W2410003069 creator A5077687541 @default.
- W2410003069 creator A5087704951 @default.
- W2410003069 creator A5088249757 @default.
- W2410003069 date "1990-05-01" @default.
- W2410003069 modified "2023-09-26" @default.
- W2410003069 title "[Pulmonary clearance of 99mTc-HMPAO aerosol]." @default.
- W2410003069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2395228" @default.
- W2410003069 hasPublicationYear "1990" @default.
- W2410003069 type Work @default.
- W2410003069 sameAs 2410003069 @default.
- W2410003069 citedByCount "0" @default.
- W2410003069 crossrefType "journal-article" @default.
- W2410003069 hasAuthorship W2410003069A5008250803 @default.
- W2410003069 hasAuthorship W2410003069A5033106552 @default.
- W2410003069 hasAuthorship W2410003069A5036610255 @default.
- W2410003069 hasAuthorship W2410003069A5050788544 @default.
- W2410003069 hasAuthorship W2410003069A5077687541 @default.
- W2410003069 hasAuthorship W2410003069A5087704951 @default.
- W2410003069 hasAuthorship W2410003069A5088249757 @default.
- W2410003069 hasConcept C126322002 @default.
- W2410003069 hasConcept C146957229 @default.
- W2410003069 hasConcept C178790620 @default.
- W2410003069 hasConcept C185592680 @default.
- W2410003069 hasConcept C2776954882 @default.
- W2410003069 hasConcept C2778136224 @default.
- W2410003069 hasConcept C2779345167 @default.
- W2410003069 hasConcept C2989005 @default.
- W2410003069 hasConcept C42219234 @default.
- W2410003069 hasConcept C522557706 @default.
- W2410003069 hasConcept C71924100 @default.
- W2410003069 hasConceptScore W2410003069C126322002 @default.
- W2410003069 hasConceptScore W2410003069C146957229 @default.
- W2410003069 hasConceptScore W2410003069C178790620 @default.
- W2410003069 hasConceptScore W2410003069C185592680 @default.
- W2410003069 hasConceptScore W2410003069C2776954882 @default.
- W2410003069 hasConceptScore W2410003069C2778136224 @default.
- W2410003069 hasConceptScore W2410003069C2779345167 @default.
- W2410003069 hasConceptScore W2410003069C2989005 @default.
- W2410003069 hasConceptScore W2410003069C42219234 @default.
- W2410003069 hasConceptScore W2410003069C522557706 @default.
- W2410003069 hasConceptScore W2410003069C71924100 @default.
- W2410003069 hasIssue "5" @default.
- W2410003069 hasLocation W24100030691 @default.
- W2410003069 hasOpenAccess W2410003069 @default.
- W2410003069 hasPrimaryLocation W24100030691 @default.
- W2410003069 hasRelatedWork W1808566151 @default.
- W2410003069 hasRelatedWork W183302643 @default.
- W2410003069 hasRelatedWork W2000501028 @default.
- W2410003069 hasRelatedWork W2012161230 @default.
- W2410003069 hasRelatedWork W2212780187 @default.
- W2410003069 hasRelatedWork W2410986564 @default.
- W2410003069 hasRelatedWork W2748952813 @default.
- W2410003069 hasRelatedWork W2899084033 @default.
- W2410003069 hasRelatedWork W2978896423 @default.
- W2410003069 hasRelatedWork W337262749 @default.
- W2410003069 hasVolume "27" @default.
- W2410003069 isParatext "false" @default.
- W2410003069 isRetracted "false" @default.
- W2410003069 magId "2410003069" @default.
- W2410003069 workType "article" @default.