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- W2410004015 abstract "Enantioselective synthesis of new anthracyclinones is reported by chiral pool synthesis, using readily available lactose or glucose as starting materials. Glycosidation of such aglycones with various carbohydrates, including or not an amino function, led to anthracyclines endowed with significant antitumor activity but having some cross-resistance with daunorubicin and doxorubicin. Lowered cross-resistance was observed when the anthracycline beared an alkyl side-chain at C-9 and a morpholinyl residue at C-4'." @default.
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- W2410004015 date "1997-01-01" @default.
- W2410004015 modified "2023-09-25" @default.
- W2410004015 title "[Enantioselective synthesis of anthracyclines]." @default.
- W2410004015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9138316" @default.
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