FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410005479> ?p ?o ?g. }

• W2410005479 endingPage "52" @default.
• W2410005479 startingPage "1145" @default.
• W2410005479 abstract "Pre-existing anti-adenovirus neutralizing antibodies (AdNAbs) are a major barrier in clinical gene therapy using adenovirus vectors; however, the transduction profile of adenovirus vectors in the presence of AdNAbs following intratumoral injection has not been fully examined, although such vectors are often intratumorally injected in clinical studies. In this study, we evaluated the correlation between the titer of AdNAbs in the serum and the transduction profiles in the tumor and the liver following intratumoral administration into mice possessing various titers of AdNAbs. Adenovirus vector-mediated transduction in the tumor was inhibited by AdNAbs; however, when the titer of AdNAbs was less than 200, the levels of inhibition in the transduction efficiencies within the tumor ranged from approximately 2- to 100-fold. A more than 2500-fold reduction of adenovirus vector-mediated transduction was found in most of the mice when the titers of AdNAbs were >200. On the other hand, the transduction efficiencies in the liver were largely reduced almost to the levels of the mock-transduced mice even at the low titers of AdNAbs. These results provide crucial information for the clinical use of adenovirus vectors." @default.
• W2410005479 created "2016-06-24" @default.
• W2410005479 creator A5011332257 @default.
• W2410005479 creator A5027498434 @default.
• W2410005479 creator A5031869546 @default.
• W2410005479 creator A5034262525 @default.
• W2410005479 date "2012-04-01" @default.
• W2410005479 modified "2023-09-26" @default.
• W2410005479 title "Correlation between adenovirus-neutralizing antibody titer and adenovirus vector-mediated transduction efficiency following intratumoral injection." @default.
• W2410005479 cites W1492631261 @default.
• W2410005479 cites W1950719160 @default.
• W2410005479 cites W1970288095 @default.
• W2410005479 cites W1970867374 @default.
• W2410005479 cites W1993408035 @default.
• W2410005479 cites W1994007686 @default.
• W2410005479 cites W1998951049 @default.
• W2410005479 cites W2002894826 @default.
• W2410005479 cites W2002912936 @default.
• W2410005479 cites W2009639644 @default.
• W2410005479 cites W2017961829 @default.
• W2410005479 cites W2019921823 @default.
• W2410005479 cites W2025822934 @default.
• W2410005479 cites W2032396826 @default.
• W2410005479 cites W2046730970 @default.
• W2410005479 cites W2052217903 @default.
• W2410005479 cites W2068026898 @default.
• W2410005479 cites W2095997476 @default.
• W2410005479 cites W2098617460 @default.
• W2410005479 cites W2098866087 @default.
• W2410005479 cites W2146108709 @default.
• W2410005479 cites W2154678088 @default.
• W2410005479 cites W2313843498 @default.
• W2410005479 cites W2322389503 @default.
• W2410005479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22493343" @default.
• W2410005479 hasPublicationYear "2012" @default.
• W2410005479 type Work @default.
• W2410005479 sameAs 2410005479 @default.
• W2410005479 citedByCount "9" @default.
• W2410005479 countsByYear W24100054792017 @default.
• W2410005479 countsByYear W24100054792018 @default.
• W2410005479 countsByYear W24100054792019 @default.
• W2410005479 countsByYear W24100054792020 @default.
• W2410005479 countsByYear W24100054792022 @default.
• W2410005479 crossrefType "journal-article" @default.
• W2410005479 hasAuthorship W2410005479A5011332257 @default.
• W2410005479 hasAuthorship W2410005479A5027498434 @default.
• W2410005479 hasAuthorship W2410005479A5031869546 @default.
• W2410005479 hasAuthorship W2410005479A5034262525 @default.
• W2410005479 hasConcept C104317684 @default.
• W2410005479 hasConcept C111599444 @default.
• W2410005479 hasConcept C15152581 @default.
• W2410005479 hasConcept C153911025 @default.
• W2410005479 hasConcept C159047783 @default.
• W2410005479 hasConcept C159654299 @default.
• W2410005479 hasConcept C203014093 @default.
• W2410005479 hasConcept C2776954459 @default.
• W2410005479 hasConcept C2779261636 @default.
• W2410005479 hasConcept C32470452 @default.
• W2410005479 hasConcept C32611913 @default.
• W2410005479 hasConcept C40767141 @default.
• W2410005479 hasConcept C55493867 @default.
• W2410005479 hasConcept C62478195 @default.
• W2410005479 hasConcept C86803240 @default.
• W2410005479 hasConcept C95444343 @default.
• W2410005479 hasConceptScore W2410005479C104317684 @default.
• W2410005479 hasConceptScore W2410005479C111599444 @default.
• W2410005479 hasConceptScore W2410005479C15152581 @default.
• W2410005479 hasConceptScore W2410005479C153911025 @default.
• W2410005479 hasConceptScore W2410005479C159047783 @default.
• W2410005479 hasConceptScore W2410005479C159654299 @default.
• W2410005479 hasConceptScore W2410005479C203014093 @default.
• W2410005479 hasConceptScore W2410005479C2776954459 @default.
• W2410005479 hasConceptScore W2410005479C2779261636 @default.
• W2410005479 hasConceptScore W2410005479C32470452 @default.
• W2410005479 hasConceptScore W2410005479C32611913 @default.
• W2410005479 hasConceptScore W2410005479C40767141 @default.
• W2410005479 hasConceptScore W2410005479C55493867 @default.
• W2410005479 hasConceptScore W2410005479C62478195 @default.
• W2410005479 hasConceptScore W2410005479C86803240 @default.
• W2410005479 hasConceptScore W2410005479C95444343 @default.
• W2410005479 hasIssue "4" @default.
• W2410005479 hasLocation W24100054791 @default.
• W2410005479 hasOpenAccess W2410005479 @default.
• W2410005479 hasPrimaryLocation W24100054791 @default.
• W2410005479 hasRelatedWork W1918885120 @default.
• W2410005479 hasRelatedWork W2014690236 @default.
• W2410005479 hasRelatedWork W2027864617 @default.
• W2410005479 hasRelatedWork W2044987256 @default.
• W2410005479 hasRelatedWork W2048927678 @default.
• W2410005479 hasRelatedWork W2058680206 @default.
• W2410005479 hasRelatedWork W2094646089 @default.
• W2410005479 hasRelatedWork W2390311273 @default.
• W2410005479 hasRelatedWork W2404091317 @default.
• W2410005479 hasRelatedWork W2410005479 @default.
• W2410005479 hasVolume "32" @default.
• W2410005479 isParatext "false" @default.
• W2410005479 isRetracted "false" @default.
• W2410005479 magId "2410005479" @default.

• next