Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410008026> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2410008026 endingPage "103" @default.
- W2410008026 startingPage "95" @default.
- W2410008026 abstract "The in vitro and in vivo effects of praziquantel on the ultrastructural surface of Opisthorchis viverrini were investigated using scanning electronmicroscopy. For the in vitro study, adult flukes were collected from experimentally infected hamsters, and were incubated for various time intervals at 37 degrees C in Earle's basal medium containing praziquantel at final concentrations of 0.01-100 micrograms/ml. For the in vivo study, flukes were collected from the biliary system of experimentally infected hamsters that had been treated 4 hours previously with 350 mg of praziquantel per kg body weight (mg/kg). Flukes were also obtained from the feces of a patient with opisthorchiasis who had been given praziquantel once at a dose of 40 mg/kg 4-6 hours previously and from the bile of a patient at the time of operation 24 hours after praziquantel treatment. Scanning electronmicroscopic analyses of the surface teguments of flukes exposed to praziquantel either in vitro or in vivo showed similar changes. Tegumental bubbles of different sizes appeared on the surface; they later ruptured and resulted in the formation of crater-like lesions. These lesions might be so extensive as to result in the peeling of the entire areas. On occasions, micronodules appeared later in these areas and those at the periphery of the lesions; these micronodules may represent an attempt by the worm to regenerate new tegument. The possibility that these ultrastructural changes may represent a generalized response of the tegumental surface to an obnoxious agent was discussed." @default.
- W2410008026 created "2016-06-24" @default.
- W2410008026 creator A5008304669 @default.
- W2410008026 creator A5012177957 @default.
- W2410008026 creator A5016324034 @default.
- W2410008026 creator A5048955963 @default.
- W2410008026 creator A5058925196 @default.
- W2410008026 creator A5070965147 @default.
- W2410008026 creator A5072453239 @default.
- W2410008026 creator A5075654389 @default.
- W2410008026 creator A5081414334 @default.
- W2410008026 date "1984-03-01" @default.
- W2410008026 modified "2023-10-14" @default.
- W2410008026 title "Alterations of the surface tegument of Opisthorchis viverrini exposed to praziquantel in vitro and in vivo." @default.
- W2410008026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6740385" @default.
- W2410008026 hasPublicationYear "1984" @default.
- W2410008026 type Work @default.
- W2410008026 sameAs 2410008026 @default.
- W2410008026 citedByCount "3" @default.
- W2410008026 crossrefType "journal-article" @default.
- W2410008026 hasAuthorship W2410008026A5008304669 @default.
- W2410008026 hasAuthorship W2410008026A5012177957 @default.
- W2410008026 hasAuthorship W2410008026A5016324034 @default.
- W2410008026 hasAuthorship W2410008026A5048955963 @default.
- W2410008026 hasAuthorship W2410008026A5058925196 @default.
- W2410008026 hasAuthorship W2410008026A5070965147 @default.
- W2410008026 hasAuthorship W2410008026A5072453239 @default.
- W2410008026 hasAuthorship W2410008026A5075654389 @default.
- W2410008026 hasAuthorship W2410008026A5081414334 @default.
- W2410008026 hasConcept C105702510 @default.
- W2410008026 hasConcept C13590703 @default.
- W2410008026 hasConcept C142724271 @default.
- W2410008026 hasConcept C146998594 @default.
- W2410008026 hasConcept C150903083 @default.
- W2410008026 hasConcept C159047783 @default.
- W2410008026 hasConcept C165901193 @default.
- W2410008026 hasConcept C202751555 @default.
- W2410008026 hasConcept C203014093 @default.
- W2410008026 hasConcept C207001950 @default.
- W2410008026 hasConcept C2776225656 @default.
- W2410008026 hasConcept C2778040090 @default.
- W2410008026 hasConcept C2779744950 @default.
- W2410008026 hasConcept C2780838300 @default.
- W2410008026 hasConcept C55493867 @default.
- W2410008026 hasConcept C71924100 @default.
- W2410008026 hasConcept C86803240 @default.
- W2410008026 hasConcept C87555872 @default.
- W2410008026 hasConceptScore W2410008026C105702510 @default.
- W2410008026 hasConceptScore W2410008026C13590703 @default.
- W2410008026 hasConceptScore W2410008026C142724271 @default.
- W2410008026 hasConceptScore W2410008026C146998594 @default.
- W2410008026 hasConceptScore W2410008026C150903083 @default.
- W2410008026 hasConceptScore W2410008026C159047783 @default.
- W2410008026 hasConceptScore W2410008026C165901193 @default.
- W2410008026 hasConceptScore W2410008026C202751555 @default.
- W2410008026 hasConceptScore W2410008026C203014093 @default.
- W2410008026 hasConceptScore W2410008026C207001950 @default.
- W2410008026 hasConceptScore W2410008026C2776225656 @default.
- W2410008026 hasConceptScore W2410008026C2778040090 @default.
- W2410008026 hasConceptScore W2410008026C2779744950 @default.
- W2410008026 hasConceptScore W2410008026C2780838300 @default.
- W2410008026 hasConceptScore W2410008026C55493867 @default.
- W2410008026 hasConceptScore W2410008026C71924100 @default.
- W2410008026 hasConceptScore W2410008026C86803240 @default.
- W2410008026 hasConceptScore W2410008026C87555872 @default.
- W2410008026 hasIssue "1" @default.
- W2410008026 hasLocation W24100080261 @default.
- W2410008026 hasOpenAccess W2410008026 @default.
- W2410008026 hasPrimaryLocation W24100080261 @default.
- W2410008026 hasRelatedWork W1529867755 @default.
- W2410008026 hasRelatedWork W1972129019 @default.
- W2410008026 hasRelatedWork W1993494935 @default.
- W2410008026 hasRelatedWork W2036346018 @default.
- W2410008026 hasRelatedWork W2054426188 @default.
- W2410008026 hasRelatedWork W2069973485 @default.
- W2410008026 hasRelatedWork W2129845076 @default.
- W2410008026 hasRelatedWork W2361752081 @default.
- W2410008026 hasRelatedWork W2410008026 @default.
- W2410008026 hasRelatedWork W2461282636 @default.
- W2410008026 hasVolume "15" @default.
- W2410008026 isParatext "false" @default.
- W2410008026 isRetracted "false" @default.
- W2410008026 magId "2410008026" @default.
- W2410008026 workType "article" @default.