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• W2410019030 abstract "EEG/fMRI takes advantage of the high temporal resolution of EEG in combination with the high spatial resolution of fMRI. These features make it particularly applicable to the study of epilepsy in which the event duration (e.g., interictal epileptiform discharges) is short, typically less than 200 milliseconds. Interictal or ictal discharges can be identified on EEG and be used for source localization in fMRI analyses. The acquisition of simultaneous EEG/fMRI involves the use of specialized EEG hardware that is safe in the MR environment and comfortable to the participant. Advanced data analysis approaches such as independent component analysis conducted alone or sometimes combined with other, e.g., Granger Causality or sliding window analyses are currently thought to be most appropriate for EEG/fMRI data. These approaches make it possible to identify networks of brain regions associated with ictal and/or interictal events allowing examination of the mechanisms critical for generation and propagation through these networks. After initial evaluation in adults, EEG/fMRI has been applied to the examination of the pediatric epilepsy syndromes including Childhood Absence Epilepsy, Benign Epilepsy with Centrotemporal Spikes (BECTS), Dravet Syndrome, and Lennox-Gastaut Syndrome. Results of EEG/fMRI studies suggest that the hemodynamic response measured by fMRI may have a different shape in response to epileptic events compared to the response to external stimuli; this may be especially true in the developing brain. Thus, the main goal of this review is to provide an overview of the pediatric applications of EEG/fMRI and its associated findings up until this point." @default.
• W2410019030 created "2016-06-24" @default.
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• W2410019030 date "2015-08-18" @default.
• W2410019030 modified "2023-09-24" @default.
• W2410019030 title "Simultaneous Electroencephalography and Functional Magnetic Resonance Imaging and the Identification of Epileptic Networks in Children" @default.
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• W2410019030 doi "https://doi.org/10.1055/s-0035-1559812" @default.
• W2410019030 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4701042" @default.
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