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- W2410088946 abstract "Overview: Breast cancer represents a biologically diverse set of diseases. Previous data suggest that the estrogen/progesterone receptor (ER/PR) status and HER2/ neu status are important determinants of prognosis and response to various systemic treatments. Recent data also suggest that these receptors correlate with outcomes of local-regional therapies. Specifically, patients with ER-positive HER2/ neu-negative disease have an excellent outcome with radiation treatments, either given as a component of breast-conservative therapy (BCT) or for those with more advanced disease, when given after mastectomy. For patients with triple-negative disease, data suggest that the proportional benefits offered from radiation in reducing local-regional recurrences may be less. This article will highlight some of these data and discuss strategies for new local-regional research avenues that are based on breast cancer biologic subtype." @default.
- W2410088946 created "2016-06-24" @default.
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- W2410088946 date "2012-06-01" @default.
- W2410088946 modified "2023-09-26" @default.
- W2410088946 title "How Does Biology Affect Local Therapy Decisions?" @default.
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- W2410088946 doi "https://doi.org/10.14694/edbook_am.2012.32.62" @default.
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