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- W2410150186 abstract "A new drug delivery system using small silica (SI) particles which can adsorb Bleomycin (BLM) and are easily transferred to the lymphatics was established to deliver a large dose of anticancer agents to the regional lymph nodes. The effects of BLM-SI, BLM solution (BLM-SOL) and saline on transplanted tumor growth and lymph node metastasis were compared in animal experiments. The inhibitory effect on tumor growth and lymph node metastasis was more remarkable in the BLM-SI group, the differences being statistically significant. The present study demonstrated that this new DDS using BLM adsorbed on SI particles was very useful for the control of transplanted tumor and lymph node metastasis." @default.
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- W2410150186 date "1995-01-01" @default.
- W2410150186 modified "2023-09-23" @default.
- W2410150186 title "Enhanced efficacy of Bleomycin adsorbed on silica particles against lymph node metastasis derived from a transplanted tumor." @default.
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