Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410160618> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2410160618 endingPage "51" @default.
- W2410160618 startingPage "339" @default.
- W2410160618 abstract "Our previous study of mitral regurgitation in obstructive hypertrophic cardiomyopathy suggested that left ventricular outflow obstruction due to systolic anterior motion of the distal residual anterior mitral leaflet may hydrodynamically induce mid-systolic mitral regurgitation. To test this hypothesis, we examined whether drug-induced left ventricular outflow obstruction in dogs might cause mitral regurgitation. Dobutamine, 20-60 micrograms/kg/min, induced the obstruction due to mitral systolic anterior motion with mitral-septal contact in 11 of 18 dogs. Pulsed Doppler and contrast echocardiography demonstrated that mitral regurgitation was concomitantly induced in the 11 dogs. The regurgitation was prominent during mid-systole from the onset to the end of mitral-septal contact. Two-dimensional echocardiography showed reduction of the mitral annular dimension and anterior shifts of the mitral valve coaptation during drug infusion in the 11 dogs. Accordingly, the distal portion of the mitral valve, especially of its anterior leaflet, became residual, and moved anteriorly in early systole and protruded into the outflow tract during mid-systole. Catheter-tip pressure recordings simultaneous with two-dimensional echocardiographic observation revealed that the outflow pressure gradient occurred across the protruding distal residual mitral valve. The onset and the end of the pressure gradient were nearly simultaneous with those of the mitral-septal contact. After cessation of the infusion, the mid-systolic mitral regurgitation disappeared together with the obstruction. These results indicate a close relationship between left ventricular outflow obstruction and mid-systolic mitral regurgitation, and strongly support the hypothesis that the obstruction due to systolic anterior motion of the distal residual anterior mitral leaflet is responsible for mitral regurgitation." @default.
- W2410160618 created "2016-06-24" @default.
- W2410160618 creator A5003545994 @default.
- W2410160618 creator A5021616375 @default.
- W2410160618 creator A5036497884 @default.
- W2410160618 creator A5052741968 @default.
- W2410160618 creator A5056582453 @default.
- W2410160618 creator A5058632588 @default.
- W2410160618 creator A5078145487 @default.
- W2410160618 creator A5089683023 @default.
- W2410160618 date "1988-06-01" @default.
- W2410160618 modified "2023-10-16" @default.
- W2410160618 title "[Correlation of left ventricular outflow obstruction with mitral regurgitation]." @default.
- W2410160618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3249262" @default.
- W2410160618 hasPublicationYear "1988" @default.
- W2410160618 type Work @default.
- W2410160618 sameAs 2410160618 @default.
- W2410160618 citedByCount "1" @default.
- W2410160618 crossrefType "journal-article" @default.
- W2410160618 hasAuthorship W2410160618A5003545994 @default.
- W2410160618 hasAuthorship W2410160618A5021616375 @default.
- W2410160618 hasAuthorship W2410160618A5036497884 @default.
- W2410160618 hasAuthorship W2410160618A5052741968 @default.
- W2410160618 hasAuthorship W2410160618A5056582453 @default.
- W2410160618 hasAuthorship W2410160618A5058632588 @default.
- W2410160618 hasAuthorship W2410160618A5078145487 @default.
- W2410160618 hasAuthorship W2410160618A5089683023 @default.
- W2410160618 hasConcept C126322002 @default.
- W2410160618 hasConcept C164705383 @default.
- W2410160618 hasConcept C169554166 @default.
- W2410160618 hasConcept C178853913 @default.
- W2410160618 hasConcept C2777361368 @default.
- W2410160618 hasConcept C2777543888 @default.
- W2410160618 hasConcept C2780225090 @default.
- W2410160618 hasConcept C2780679668 @default.
- W2410160618 hasConcept C2780864736 @default.
- W2410160618 hasConcept C2781185063 @default.
- W2410160618 hasConcept C2993373945 @default.
- W2410160618 hasConcept C57900726 @default.
- W2410160618 hasConcept C71924100 @default.
- W2410160618 hasConcept C84393581 @default.
- W2410160618 hasConceptScore W2410160618C126322002 @default.
- W2410160618 hasConceptScore W2410160618C164705383 @default.
- W2410160618 hasConceptScore W2410160618C169554166 @default.
- W2410160618 hasConceptScore W2410160618C178853913 @default.
- W2410160618 hasConceptScore W2410160618C2777361368 @default.
- W2410160618 hasConceptScore W2410160618C2777543888 @default.
- W2410160618 hasConceptScore W2410160618C2780225090 @default.
- W2410160618 hasConceptScore W2410160618C2780679668 @default.
- W2410160618 hasConceptScore W2410160618C2780864736 @default.
- W2410160618 hasConceptScore W2410160618C2781185063 @default.
- W2410160618 hasConceptScore W2410160618C2993373945 @default.
- W2410160618 hasConceptScore W2410160618C57900726 @default.
- W2410160618 hasConceptScore W2410160618C71924100 @default.
- W2410160618 hasConceptScore W2410160618C84393581 @default.
- W2410160618 hasIssue "2" @default.
- W2410160618 hasLocation W24101606181 @default.
- W2410160618 hasOpenAccess W2410160618 @default.
- W2410160618 hasPrimaryLocation W24101606181 @default.
- W2410160618 hasRelatedWork W1999709300 @default.
- W2410160618 hasRelatedWork W2074569189 @default.
- W2410160618 hasRelatedWork W2090876786 @default.
- W2410160618 hasRelatedWork W2339900482 @default.
- W2410160618 hasRelatedWork W2399339069 @default.
- W2410160618 hasRelatedWork W2410160618 @default.
- W2410160618 hasRelatedWork W2615516258 @default.
- W2410160618 hasRelatedWork W3011367210 @default.
- W2410160618 hasRelatedWork W3029736894 @default.
- W2410160618 hasRelatedWork W3203706372 @default.
- W2410160618 hasVolume "18" @default.
- W2410160618 isParatext "false" @default.
- W2410160618 isRetracted "false" @default.
- W2410160618 magId "2410160618" @default.
- W2410160618 workType "article" @default.