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- W2410277616 abstract "Three new polyketides, trichocladinols I-K (1-3) with oxabicyclic (1 and 3) and oxatricyclic (2) skeletons, together with three known metabolites, massarilactone G (4), massarigenin D (5), and rosigenin (6), were isolated from the solid-substrate fermentation cultures of the ascomycete fungus Trichocladium opacum. The structures of the new compounds were elucidated primarily by analysis of NMR data. The absolute configurations of 1-3 were deduced from circular dichroism (CD) data. Compounds 1-3 were tested for cytotoxicity against five human carcinoma cell lines, HeLa, A549, MCF-7, HCT116, and T24. Compound 1 showed a weak cytotoxic effect against HeLa cells, but 2 and 3 were inactive." @default.
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- W2410277616 date "2014-05-01" @default.
- W2410277616 modified "2023-09-23" @default.
- W2410277616 title "Trichocladinols I-K, Oxatricyclic and Oxabicyclic Polyketides from Trichocladium opacum" @default.
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- W2410277616 doi "https://doi.org/10.1177/1934578x1400900528" @default.
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