FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410312981> ?p ?o ?g. }

• W2410312981 endingPage "25" @default.
• W2410312981 startingPage "217" @default.
• W2410312981 abstract "The human Fc gamma RIIA gene produces multiple transcripts, including those with (Fc gamma RIIa1) and without (Fc gamma RIIa2) the single exon encoding the transmembrane domain (TM). Previously, a fluorescence-based RT-PCR assay showed lineage-specific differences in Fc gamma RIIA transcript ratios (Fc gamma RIIa2/Fc gamma RIIa1). The mechanism of this lineage-specific expression was investigated in this study. Differential transcript stability does not play a major role, because transcript ratios remained constant in cells with both low (K562) and high (Dami) ratios following actinomycin D treatment. Transient expression studies in K562 and Dami cells using a minigene construct containing a 5.0 kb genomic fragment including the TM exon and adjacent intron and exon sequences showed recapitulation of endogenous transcript ratios. The TM exon was efficiently spliced in by the constitutive splicing machinery in HeLa cells, an Fc gamma RIIA-negative cell line. Lineage-specific TM exon skipping was markedly diminished by two independent minigene mutations: a point mutation of the first nucleotide of the TM exon, and a five basepair intronic deletion near a putative branchpoint. These data demonstrate that cis-acting sequences in or near the TM exon 3' splice acceptor site contribute to lineage-specific differences in Fc gamma RIIA transcript ratios." @default.
• W2410312981 created "2016-06-24" @default.
• W2410312981 creator A5021835757 @default.
• W2410312981 creator A5038834229 @default.
• W2410312981 creator A5052240136 @default.
• W2410312981 creator A5075699991 @default.
• W2410312981 creator A5079666354 @default.
• W2410312981 creator A5090377432 @default.
• W2410312981 date "1995-01-01" @default.
• W2410312981 modified "2023-09-23" @default.
• W2410312981 title "Lineage-specific alternative splicing of the human Fc gamma RIIA transmembrane exon requires sequences near the 3' splice site." @default.
• W2410312981 cites W1515351996 @default.
• W2410312981 cites W1532508263 @default.
• W2410312981 cites W1883746954 @default.
• W2410312981 cites W1971956957 @default.
• W2410312981 cites W1989237539 @default.
• W2410312981 cites W1994031775 @default.
• W2410312981 cites W2007694375 @default.
• W2410312981 cites W2014188205 @default.
• W2410312981 cites W2020446308 @default.
• W2410312981 cites W2023218737 @default.
• W2410312981 cites W2023236405 @default.
• W2410312981 cites W2034193185 @default.
• W2410312981 cites W2048371926 @default.
• W2410312981 cites W2053142169 @default.
• W2410312981 cites W2053205591 @default.
• W2410312981 cites W2060913542 @default.
• W2410312981 cites W2072488277 @default.
• W2410312981 cites W2082127202 @default.
• W2410312981 cites W2091943511 @default.
• W2410312981 cites W2094975773 @default.
• W2410312981 cites W2095543650 @default.
• W2410312981 cites W2097794242 @default.
• W2410312981 cites W2115149771 @default.
• W2410312981 cites W2120315535 @default.
• W2410312981 cites W2120608329 @default.
• W2410312981 cites W2122200639 @default.
• W2410312981 cites W2133143001 @default.
• W2410312981 cites W2137185605 @default.
• W2410312981 cites W2143585655 @default.
• W2410312981 cites W2147964313 @default.
• W2410312981 cites W2151062280 @default.
• W2410312981 cites W2151078655 @default.
• W2410312981 cites W2151657407 @default.
• W2410312981 cites W2264365292 @default.
• W2410312981 cites W2396597594 @default.
• W2410312981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6134390" @default.
• W2410312981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7787414" @default.
• W2410312981 hasPublicationYear "1995" @default.
• W2410312981 type Work @default.
• W2410312981 sameAs 2410312981 @default.
• W2410312981 citedByCount "1" @default.
• W2410312981 crossrefType "journal-article" @default.
• W2410312981 hasAuthorship W2410312981A5021835757 @default.
• W2410312981 hasAuthorship W2410312981A5038834229 @default.
• W2410312981 hasAuthorship W2410312981A5052240136 @default.
• W2410312981 hasAuthorship W2410312981A5075699991 @default.
• W2410312981 hasAuthorship W2410312981A5079666354 @default.
• W2410312981 hasAuthorship W2410312981A5090377432 @default.
• W2410312981 hasConcept C104317684 @default.
• W2410312981 hasConcept C153911025 @default.
• W2410312981 hasConcept C166342232 @default.
• W2410312981 hasConcept C194583182 @default.
• W2410312981 hasConcept C2776817793 @default.
• W2410312981 hasConcept C2778776201 @default.
• W2410312981 hasConcept C36823959 @default.
• W2410312981 hasConcept C54355233 @default.
• W2410312981 hasConcept C54458228 @default.
• W2410312981 hasConcept C62257209 @default.
• W2410312981 hasConcept C67705224 @default.
• W2410312981 hasConcept C86803240 @default.
• W2410312981 hasConcept C94671646 @default.
• W2410312981 hasConceptScore W2410312981C104317684 @default.
• W2410312981 hasConceptScore W2410312981C153911025 @default.
• W2410312981 hasConceptScore W2410312981C166342232 @default.
• W2410312981 hasConceptScore W2410312981C194583182 @default.
• W2410312981 hasConceptScore W2410312981C2776817793 @default.
• W2410312981 hasConceptScore W2410312981C2778776201 @default.
• W2410312981 hasConceptScore W2410312981C36823959 @default.
• W2410312981 hasConceptScore W2410312981C54355233 @default.
• W2410312981 hasConceptScore W2410312981C54458228 @default.
• W2410312981 hasConceptScore W2410312981C62257209 @default.
• W2410312981 hasConceptScore W2410312981C67705224 @default.
• W2410312981 hasConceptScore W2410312981C86803240 @default.
• W2410312981 hasConceptScore W2410312981C94671646 @default.
• W2410312981 hasIssue "4-5" @default.
• W2410312981 hasLocation W24103129811 @default.
• W2410312981 hasOpenAccess W2410312981 @default.
• W2410312981 hasPrimaryLocation W24103129811 @default.
• W2410312981 hasRelatedWork W2013123757 @default.
• W2410312981 hasRelatedWork W2034398488 @default.
• W2410312981 hasRelatedWork W2120243182 @default.
• W2410312981 hasRelatedWork W2144655298 @default.
• W2410312981 hasRelatedWork W2154467209 @default.
• W2410312981 hasRelatedWork W2410312981 @default.
• W2410312981 hasRelatedWork W2601318190 @default.
• W2410312981 hasRelatedWork W2796118888 @default.
• W2410312981 hasRelatedWork W3034349485 @default.

• next