Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410341838> ?p ?o ?g. }
- W2410341838 endingPage "175" @default.
- W2410341838 startingPage "169" @default.
- W2410341838 abstract "Introduction The diagnostic and prognostic value of immature platelet fraction (IPF) in sepsis has not been determined. This study aimed to assess whether IPF is an early predictor of platelet decline due to coagulopathy and is associated with mortality in patients with sepsis. Materials and methods In total, 149 patients with a platelet count of ≥80 × 103/μL on intensive care unit admission (101 with sepsis, 48 controls without sepsis) were prospectively evaluated. We measured IPF on admission and observed for development of subsequent platelet count decline (defined as a >30% decrease or <80 × 103/μL) in 5 days, and mortality at 28 days. The absolute immature platelet count (AIPC) was calculated to evaluate thrombopoiesis. Results Forty-seven patients with sepsis subsequently developed a decrease in platelet count. The IPF was highest in patients whose platelet count decreased, followed by patients without a decrease in platelet count and controls (median, 4.3% [3.1%–8.1%] vs. 3.7% [2.6%–4.6%] vs. 2.1% [1.6%–3.5%], respectively; P < 0.0001). The AIPC was similar in patients with and without a decrease in platelet count (7.6 [4.2–10.0] vs. 5.9 [4.2–8.7] × 103/μL, respectively; P = 0.32). Coagulation derangement was more severe in patients who did than did not subsequently develop a decreased platelet count. Cox regression and receiver operator characteristic curve analysis revealed that IPF was a strong independent predictor of mortality, with accuracy similar to a standard prognostic scoring system. Conclusions The admission IPF in septic patients predicts a subsequent decrease in platelet count, indicating platelet consumption with ongoing coagulopathy and risk of poor prognosis." @default.
- W2410341838 created "2016-06-24" @default.
- W2410341838 creator A5001775532 @default.
- W2410341838 creator A5024806414 @default.
- W2410341838 creator A5038625625 @default.
- W2410341838 creator A5042583909 @default.
- W2410341838 creator A5045283891 @default.
- W2410341838 creator A5059512701 @default.
- W2410341838 creator A5081925376 @default.
- W2410341838 creator A5087990902 @default.
- W2410341838 date "2016-08-01" @default.
- W2410341838 modified "2023-09-30" @default.
- W2410341838 title "Immature platelet fraction predicts coagulopathy-related platelet consumption and mortality in patients with sepsis" @default.
- W2410341838 cites W1898928487 @default.
- W2410341838 cites W1967561904 @default.
- W2410341838 cites W1968652207 @default.
- W2410341838 cites W1972113004 @default.
- W2410341838 cites W1973827664 @default.
- W2410341838 cites W1974478868 @default.
- W2410341838 cites W1978737655 @default.
- W2410341838 cites W1987775704 @default.
- W2410341838 cites W1987893175 @default.
- W2410341838 cites W1989528047 @default.
- W2410341838 cites W1993220550 @default.
- W2410341838 cites W2003876414 @default.
- W2410341838 cites W2021181719 @default.
- W2410341838 cites W2021420366 @default.
- W2410341838 cites W2029271298 @default.
- W2410341838 cites W2032098384 @default.
- W2410341838 cites W2065356252 @default.
- W2410341838 cites W2067320587 @default.
- W2410341838 cites W2088876970 @default.
- W2410341838 cites W2094189464 @default.
- W2410341838 cites W2098382509 @default.
- W2410341838 cites W2118858814 @default.
- W2410341838 cites W2129921286 @default.
- W2410341838 cites W2136735792 @default.
- W2410341838 cites W2137320564 @default.
- W2410341838 cites W2152731734 @default.
- W2410341838 cites W2157562993 @default.
- W2410341838 cites W2159047625 @default.
- W2410341838 cites W2160950389 @default.
- W2410341838 cites W2161370760 @default.
- W2410341838 cites W2172713615 @default.
- W2410341838 cites W2314787815 @default.
- W2410341838 cites W2442246762 @default.
- W2410341838 cites W28106649 @default.
- W2410341838 cites W335124151 @default.
- W2410341838 cites W4293242440 @default.
- W2410341838 doi "https://doi.org/10.1016/j.thromres.2016.06.002" @default.
- W2410341838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27380496" @default.
- W2410341838 hasPublicationYear "2016" @default.
- W2410341838 type Work @default.
- W2410341838 sameAs 2410341838 @default.
- W2410341838 citedByCount "37" @default.
- W2410341838 countsByYear W24103418382017 @default.
- W2410341838 countsByYear W24103418382018 @default.
- W2410341838 countsByYear W24103418382019 @default.
- W2410341838 countsByYear W24103418382020 @default.
- W2410341838 countsByYear W24103418382021 @default.
- W2410341838 countsByYear W24103418382022 @default.
- W2410341838 countsByYear W24103418382023 @default.
- W2410341838 crossrefType "journal-article" @default.
- W2410341838 hasAuthorship W2410341838A5001775532 @default.
- W2410341838 hasAuthorship W2410341838A5024806414 @default.
- W2410341838 hasAuthorship W2410341838A5038625625 @default.
- W2410341838 hasAuthorship W2410341838A5042583909 @default.
- W2410341838 hasAuthorship W2410341838A5045283891 @default.
- W2410341838 hasAuthorship W2410341838A5059512701 @default.
- W2410341838 hasAuthorship W2410341838A5081925376 @default.
- W2410341838 hasAuthorship W2410341838A5087990902 @default.
- W2410341838 hasConcept C109159458 @default.
- W2410341838 hasConcept C126322002 @default.
- W2410341838 hasConcept C190481736 @default.
- W2410341838 hasConcept C2776376669 @default.
- W2410341838 hasConcept C2776689292 @default.
- W2410341838 hasConcept C2776958478 @default.
- W2410341838 hasConcept C2778384902 @default.
- W2410341838 hasConcept C2779705218 @default.
- W2410341838 hasConcept C2779936836 @default.
- W2410341838 hasConcept C28328180 @default.
- W2410341838 hasConcept C54355233 @default.
- W2410341838 hasConcept C71924100 @default.
- W2410341838 hasConcept C86803240 @default.
- W2410341838 hasConcept C89560881 @default.
- W2410341838 hasConcept C90924648 @default.
- W2410341838 hasConceptScore W2410341838C109159458 @default.
- W2410341838 hasConceptScore W2410341838C126322002 @default.
- W2410341838 hasConceptScore W2410341838C190481736 @default.
- W2410341838 hasConceptScore W2410341838C2776376669 @default.
- W2410341838 hasConceptScore W2410341838C2776689292 @default.
- W2410341838 hasConceptScore W2410341838C2776958478 @default.
- W2410341838 hasConceptScore W2410341838C2778384902 @default.
- W2410341838 hasConceptScore W2410341838C2779705218 @default.
- W2410341838 hasConceptScore W2410341838C2779936836 @default.
- W2410341838 hasConceptScore W2410341838C28328180 @default.
- W2410341838 hasConceptScore W2410341838C54355233 @default.
- W2410341838 hasConceptScore W2410341838C71924100 @default.