Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410360126> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2410360126 endingPage "22" @default.
- W2410360126 startingPage "1017" @default.
- W2410360126 abstract "To explore an efficient strategy for further development of anticancer fluoroquinolone candidates derived from ciprofloxacin, a heterocyclic ring as the bioisosteric replacement of C3 carboxyl group led to a key intermediate, oxadiazole thiol (5), which was further modified to the bis-oxadiazole methylsulfides (7a-7h) and the corresponding dimethylpiperazinium iodides (8a-8h), respectively. Structures were characterized by elemental analysis and spectra data, and their anticancer activities in vitro against CHO, HL60 and L1210 cancer cells were also evaluated by MTT assay. The preliminary results show that piperazinium compounds (8) possess more potent activity than that of corresponding free bases (7)." @default.
- W2410360126 created "2016-06-24" @default.
- W2410360126 creator A5017179393 @default.
- W2410360126 creator A5019091031 @default.
- W2410360126 creator A5035843312 @default.
- W2410360126 creator A5046597133 @default.
- W2410360126 creator A5050664552 @default.
- W2410360126 creator A5077092010 @default.
- W2410360126 creator A5079645945 @default.
- W2410360126 creator A5089572644 @default.
- W2410360126 creator A5091785494 @default.
- W2410360126 creator A5091804991 @default.
- W2410360126 date "2012-08-01" @default.
- W2410360126 modified "2023-09-26" @default.
- W2410360126 title "Part IV: Design, synthesis and antitumor activity of fluoroquinolone C-3 heterocycles: bis-oxadiazole methylsulfide derivatives derived from ciprofloxacin." @default.
- W2410360126 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23162898" @default.
- W2410360126 hasPublicationYear "2012" @default.
- W2410360126 type Work @default.
- W2410360126 sameAs 2410360126 @default.
- W2410360126 citedByCount "3" @default.
- W2410360126 countsByYear W24103601262016 @default.
- W2410360126 countsByYear W24103601262023 @default.
- W2410360126 crossrefType "journal-article" @default.
- W2410360126 hasAuthorship W2410360126A5017179393 @default.
- W2410360126 hasAuthorship W2410360126A5019091031 @default.
- W2410360126 hasAuthorship W2410360126A5035843312 @default.
- W2410360126 hasAuthorship W2410360126A5046597133 @default.
- W2410360126 hasAuthorship W2410360126A5050664552 @default.
- W2410360126 hasAuthorship W2410360126A5077092010 @default.
- W2410360126 hasAuthorship W2410360126A5079645945 @default.
- W2410360126 hasAuthorship W2410360126A5089572644 @default.
- W2410360126 hasAuthorship W2410360126A5091785494 @default.
- W2410360126 hasAuthorship W2410360126A5091804991 @default.
- W2410360126 hasConcept C178790620 @default.
- W2410360126 hasConcept C185592680 @default.
- W2410360126 hasConcept C202751555 @default.
- W2410360126 hasConcept C21951064 @default.
- W2410360126 hasConcept C2778512257 @default.
- W2410360126 hasConcept C2779448499 @default.
- W2410360126 hasConcept C2780783641 @default.
- W2410360126 hasConcept C501593827 @default.
- W2410360126 hasConcept C55493867 @default.
- W2410360126 hasConcept C71240020 @default.
- W2410360126 hasConceptScore W2410360126C178790620 @default.
- W2410360126 hasConceptScore W2410360126C185592680 @default.
- W2410360126 hasConceptScore W2410360126C202751555 @default.
- W2410360126 hasConceptScore W2410360126C21951064 @default.
- W2410360126 hasConceptScore W2410360126C2778512257 @default.
- W2410360126 hasConceptScore W2410360126C2779448499 @default.
- W2410360126 hasConceptScore W2410360126C2780783641 @default.
- W2410360126 hasConceptScore W2410360126C501593827 @default.
- W2410360126 hasConceptScore W2410360126C55493867 @default.
- W2410360126 hasConceptScore W2410360126C71240020 @default.
- W2410360126 hasIssue "8" @default.
- W2410360126 hasLocation W24103601261 @default.
- W2410360126 hasOpenAccess W2410360126 @default.
- W2410360126 hasPrimaryLocation W24103601261 @default.
- W2410360126 hasRelatedWork W1992477696 @default.
- W2410360126 hasRelatedWork W2122333470 @default.
- W2410360126 hasRelatedWork W2395621549 @default.
- W2410360126 hasRelatedWork W2410360126 @default.
- W2410360126 hasRelatedWork W2605630098 @default.
- W2410360126 hasRelatedWork W2950723608 @default.
- W2410360126 hasRelatedWork W2950966945 @default.
- W2410360126 hasRelatedWork W2950990276 @default.
- W2410360126 hasRelatedWork W2952009292 @default.
- W2410360126 hasRelatedWork W2953075148 @default.
- W2410360126 hasVolume "47" @default.
- W2410360126 isParatext "false" @default.
- W2410360126 isRetracted "false" @default.
- W2410360126 magId "2410360126" @default.
- W2410360126 workType "article" @default.