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- W2410378993 abstract "The physicians and the women were disturbed by recent communications discussing a possible relationship between the postmenopausal application of estrogens and endometrial carcinoma. An analysis of these reports is made critically and in detail. The practical aspects are delineated and a precise guide to postmenopausal estrogen therapy is presented.An analysis is made of 3 reports of American studies which linked the postmenopausal use of estrogens to endometrial cancer. In regard to the accuracy of these studies, the author emphasizes that proper attention must be paid 1st to the state of those subjects in the control group and, more importantly, to the presence of other risk factors in the patients. Most disorders and diseases in which estrogens are employed as therapy are also noted to be risk factors in the diagnosis of endometrial carcinoma. These include adiposity, diabetes, high blood pressure, infertility, prolonged cyclical disruptions, menopause, and the social status of the patient (in which the increased use of estrogens and other possible carcinogens is noted to exceed that of poorer class patients). The possible dangers of the use of estrogens are recognized, however, and must certainly be particularly considered when the patient shows 1 or more other risk factors. A guideline for postmenopausal administration of estrogens is given." @default.
- W2410378993 created "2016-06-24" @default.
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- W2410378993 date "1976-12-02" @default.
- W2410378993 modified "2023-09-23" @default.
- W2410378993 title "[Estrogens and carcinoma of the endometrium]." @default.
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