Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410448071> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2410448071 endingPage "18" @default.
- W2410448071 startingPage "109" @default.
- W2410448071 abstract "The latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus (KSHV) plays a key role in the induction of cell transformation, maintenance of viral episome, and modulation of immune response in human. To identify the presence of B cell epitopes within C-terminus of LANA and to characterize the monoclonal antibodies (MAbs) against this protein, we expressed the C-terminal region at aa 794-1000 of LANA (pLANA-C) in Escherichia coli as a fusion protein. KSHV-positive human sera were able to recognize the recombinant LANA-C in the Western blot analysis and ELISA. Mapping of antigenic epitopes of pLANA-C by KSHV-positive human sera revealed two B cell antigenic epitopes located at aa 846-854 and aa 794-822. The MAb 3F11 recognized a region between at aa 840 to 846 of LANA and exhibited a strong and specific binding to both pLANA-C and native viral LANA. These findings showed that pLANA-C and MAb 3F11 could be used for the detection of KSHV antibodies in human sera and for the advanced study of biological functions of LANA." @default.
- W2410448071 created "2016-06-24" @default.
- W2410448071 creator A5037945468 @default.
- W2410448071 creator A5040049353 @default.
- W2410448071 creator A5043748613 @default.
- W2410448071 creator A5047605330 @default.
- W2410448071 creator A5049924861 @default.
- W2410448071 creator A5055965341 @default.
- W2410448071 creator A5061178696 @default.
- W2410448071 creator A5069495912 @default.
- W2410448071 date "2007-01-01" @default.
- W2410448071 modified "2023-09-23" @default.
- W2410448071 title "Identification of B cell epitopes at the C-terminus of latency-associated nuclear protein of the kaposi's sarcoma-associated herpesvirus." @default.
- W2410448071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17900217" @default.
- W2410448071 hasPublicationYear "2007" @default.
- W2410448071 type Work @default.
- W2410448071 sameAs 2410448071 @default.
- W2410448071 citedByCount "0" @default.
- W2410448071 crossrefType "journal-article" @default.
- W2410448071 hasAuthorship W2410448071A5037945468 @default.
- W2410448071 hasAuthorship W2410448071A5040049353 @default.
- W2410448071 hasAuthorship W2410448071A5043748613 @default.
- W2410448071 hasAuthorship W2410448071A5047605330 @default.
- W2410448071 hasAuthorship W2410448071A5049924861 @default.
- W2410448071 hasAuthorship W2410448071A5055965341 @default.
- W2410448071 hasAuthorship W2410448071A5061178696 @default.
- W2410448071 hasAuthorship W2410448071A5069495912 @default.
- W2410448071 hasConcept C104317684 @default.
- W2410448071 hasConcept C123894998 @default.
- W2410448071 hasConcept C147483822 @default.
- W2410448071 hasConcept C153911025 @default.
- W2410448071 hasConcept C159047783 @default.
- W2410448071 hasConcept C159654299 @default.
- W2410448071 hasConcept C195616568 @default.
- W2410448071 hasConcept C203014093 @default.
- W2410448071 hasConcept C2522874641 @default.
- W2410448071 hasConcept C2776409557 @default.
- W2410448071 hasConcept C2776415932 @default.
- W2410448071 hasConcept C2780727368 @default.
- W2410448071 hasConcept C2780797929 @default.
- W2410448071 hasConcept C40767141 @default.
- W2410448071 hasConcept C542903549 @default.
- W2410448071 hasConcept C54355233 @default.
- W2410448071 hasConcept C86803240 @default.
- W2410448071 hasConceptScore W2410448071C104317684 @default.
- W2410448071 hasConceptScore W2410448071C123894998 @default.
- W2410448071 hasConceptScore W2410448071C147483822 @default.
- W2410448071 hasConceptScore W2410448071C153911025 @default.
- W2410448071 hasConceptScore W2410448071C159047783 @default.
- W2410448071 hasConceptScore W2410448071C159654299 @default.
- W2410448071 hasConceptScore W2410448071C195616568 @default.
- W2410448071 hasConceptScore W2410448071C203014093 @default.
- W2410448071 hasConceptScore W2410448071C2522874641 @default.
- W2410448071 hasConceptScore W2410448071C2776409557 @default.
- W2410448071 hasConceptScore W2410448071C2776415932 @default.
- W2410448071 hasConceptScore W2410448071C2780727368 @default.
- W2410448071 hasConceptScore W2410448071C2780797929 @default.
- W2410448071 hasConceptScore W2410448071C40767141 @default.
- W2410448071 hasConceptScore W2410448071C542903549 @default.
- W2410448071 hasConceptScore W2410448071C54355233 @default.
- W2410448071 hasConceptScore W2410448071C86803240 @default.
- W2410448071 hasIssue "2" @default.
- W2410448071 hasLocation W24104480711 @default.
- W2410448071 hasOpenAccess W2410448071 @default.
- W2410448071 hasPrimaryLocation W24104480711 @default.
- W2410448071 hasRelatedWork W1988955679 @default.
- W2410448071 hasRelatedWork W2026887472 @default.
- W2410448071 hasRelatedWork W2029042089 @default.
- W2410448071 hasRelatedWork W2074545760 @default.
- W2410448071 hasRelatedWork W2115868555 @default.
- W2410448071 hasRelatedWork W2161757555 @default.
- W2410448071 hasRelatedWork W2347529241 @default.
- W2410448071 hasRelatedWork W2378541398 @default.
- W2410448071 hasRelatedWork W2410251327 @default.
- W2410448071 hasRelatedWork W45495513 @default.
- W2410448071 hasVolume "51" @default.
- W2410448071 isParatext "false" @default.
- W2410448071 isRetracted "false" @default.
- W2410448071 magId "2410448071" @default.
- W2410448071 workType "article" @default.