Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410527603> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2410527603 endingPage "4" @default.
- W2410527603 startingPage "21" @default.
- W2410527603 abstract "To study the influence of HBV/P22 protein on the induced apoptosis of HepG2 cells.In vitro, two HepG2 strains were transfected with pcDNA3.1+ and pcDNA3.1+HBV/P22 respectively and the cells were exposed to Act D and TNF alpha for 6h and then the induced apoptosis was detected by flow cytometry (FCM) and TUNEL technique. Supernatant HBeAg was detected by Abbott reagent. The intracellular expression of HBV/P22 protein was measured by Western blot and immunochemistry. In vivo, three cell groups were inoculated into nude mice by subcutaneous injections. After two weeks, Act D and TNF alpha were injected into the tumors and then the induced apoptosis in the tissues was detected by TUNEL technique. The expression of HBV/P22 protein in the tumor tissues was detected by immunochemistry.In vitro, in HepG2- pcDNA3.1+HBV/P22 cells, supernatant HBeAg was positive and intracellular HBV/P22 protein was positively expressed. The apoptosis proportion of HepG2-pCDNA3.1+HBV/P22 cells was markedly lower than HepG2 and HepG2-pcDNA3.1+ cells (P < 0.05). In vivo, HBV/P22 protein was expressed in the tumor tissues, and the apoptosis proportion in the group injected with HepG2-pcDNA3.1+HBV/P22 cells was markedly lower than those injected with HepG2 and HepG2-pcDNA3.1+cells (P < 0.05).HBV/P22 protein could inhibit the induced apoptosis of HepG2 cells both in vitro and in vivo." @default.
- W2410527603 created "2016-06-24" @default.
- W2410527603 creator A5008080453 @default.
- W2410527603 creator A5020122413 @default.
- W2410527603 creator A5021386765 @default.
- W2410527603 creator A5074018909 @default.
- W2410527603 creator A5084332512 @default.
- W2410527603 date "2008-01-01" @default.
- W2410527603 modified "2023-10-01" @default.
- W2410527603 title "[The influence of HBV/P22 protein on the apoptosis of HepG2 cells: an experimental study]." @default.
- W2410527603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18226338" @default.
- W2410527603 hasPublicationYear "2008" @default.
- W2410527603 type Work @default.
- W2410527603 sameAs 2410527603 @default.
- W2410527603 citedByCount "1" @default.
- W2410527603 countsByYear W24105276032023 @default.
- W2410527603 crossrefType "journal-article" @default.
- W2410527603 hasAuthorship W2410527603A5008080453 @default.
- W2410527603 hasAuthorship W2410527603A5020122413 @default.
- W2410527603 hasAuthorship W2410527603A5021386765 @default.
- W2410527603 hasAuthorship W2410527603A5074018909 @default.
- W2410527603 hasAuthorship W2410527603A5084332512 @default.
- W2410527603 hasConcept C104317684 @default.
- W2410527603 hasConcept C150903083 @default.
- W2410527603 hasConcept C153911025 @default.
- W2410527603 hasConcept C159047783 @default.
- W2410527603 hasConcept C159654299 @default.
- W2410527603 hasConcept C185592680 @default.
- W2410527603 hasConcept C190283241 @default.
- W2410527603 hasConcept C196795494 @default.
- W2410527603 hasConcept C202751555 @default.
- W2410527603 hasConcept C203014093 @default.
- W2410527603 hasConcept C207001950 @default.
- W2410527603 hasConcept C2522874641 @default.
- W2410527603 hasConcept C2775940106 @default.
- W2410527603 hasConcept C2776415932 @default.
- W2410527603 hasConcept C2777410769 @default.
- W2410527603 hasConcept C2780593183 @default.
- W2410527603 hasConcept C2780659158 @default.
- W2410527603 hasConcept C54009773 @default.
- W2410527603 hasConcept C54355233 @default.
- W2410527603 hasConcept C553184892 @default.
- W2410527603 hasConcept C55493867 @default.
- W2410527603 hasConcept C81885089 @default.
- W2410527603 hasConcept C86803240 @default.
- W2410527603 hasConceptScore W2410527603C104317684 @default.
- W2410527603 hasConceptScore W2410527603C150903083 @default.
- W2410527603 hasConceptScore W2410527603C153911025 @default.
- W2410527603 hasConceptScore W2410527603C159047783 @default.
- W2410527603 hasConceptScore W2410527603C159654299 @default.
- W2410527603 hasConceptScore W2410527603C185592680 @default.
- W2410527603 hasConceptScore W2410527603C190283241 @default.
- W2410527603 hasConceptScore W2410527603C196795494 @default.
- W2410527603 hasConceptScore W2410527603C202751555 @default.
- W2410527603 hasConceptScore W2410527603C203014093 @default.
- W2410527603 hasConceptScore W2410527603C207001950 @default.
- W2410527603 hasConceptScore W2410527603C2522874641 @default.
- W2410527603 hasConceptScore W2410527603C2775940106 @default.
- W2410527603 hasConceptScore W2410527603C2776415932 @default.
- W2410527603 hasConceptScore W2410527603C2777410769 @default.
- W2410527603 hasConceptScore W2410527603C2780593183 @default.
- W2410527603 hasConceptScore W2410527603C2780659158 @default.
- W2410527603 hasConceptScore W2410527603C54009773 @default.
- W2410527603 hasConceptScore W2410527603C54355233 @default.
- W2410527603 hasConceptScore W2410527603C553184892 @default.
- W2410527603 hasConceptScore W2410527603C55493867 @default.
- W2410527603 hasConceptScore W2410527603C81885089 @default.
- W2410527603 hasConceptScore W2410527603C86803240 @default.
- W2410527603 hasIssue "1" @default.
- W2410527603 hasLocation W24105276031 @default.
- W2410527603 hasOpenAccess W2410527603 @default.
- W2410527603 hasPrimaryLocation W24105276031 @default.
- W2410527603 hasRelatedWork W2149292227 @default.
- W2410527603 hasRelatedWork W2175105932 @default.
- W2410527603 hasRelatedWork W2337728256 @default.
- W2410527603 hasRelatedWork W2349196639 @default.
- W2410527603 hasRelatedWork W2362374407 @default.
- W2410527603 hasRelatedWork W2367501680 @default.
- W2410527603 hasRelatedWork W2369745628 @default.
- W2410527603 hasRelatedWork W2375549177 @default.
- W2410527603 hasRelatedWork W2376660410 @default.
- W2410527603 hasRelatedWork W2385361523 @default.
- W2410527603 hasRelatedWork W2404847964 @default.
- W2410527603 hasRelatedWork W2436535660 @default.
- W2410527603 hasRelatedWork W2587501126 @default.
- W2410527603 hasRelatedWork W2745845876 @default.
- W2410527603 hasRelatedWork W3029880360 @default.
- W2410527603 hasRelatedWork W3031284047 @default.
- W2410527603 hasRelatedWork W3143478086 @default.
- W2410527603 hasRelatedWork W3147590166 @default.
- W2410527603 hasRelatedWork W3149066013 @default.
- W2410527603 hasRelatedWork W1900427498 @default.
- W2410527603 hasVolume "16" @default.
- W2410527603 isParatext "false" @default.
- W2410527603 isRetracted "false" @default.
- W2410527603 magId "2410527603" @default.
- W2410527603 workType "article" @default.