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- W2410548530 abstract "The prophylactic effect of intraoperative one shot antibiotic application in colorectal surgery was investigated. Patients were randomised and the antibiotic combination Mezlocillin/Metronidazole (group A) or Amoxicillin/Clavulamid acid (group B) was applicated in 160 patients. 111 patients were selected for the study (group A: 59; group B: 52 patients). In the postoperative course 53% (group A) and 67% (group B) of the patients developed bacterial infections. Abdominal wound healing was complicated by infection in 15% (A) and 12% (B) of the patients. A significant difference between the two groups could not be proven, 24% of all patients with documented intraoperative bacterial contamination and 10% of the patients with negative findings developed wound infections. In colorectal surgery patients are still at high risk for infectious complications. Applicated antibiotics should basically cover aerobic and anaerobic germs." @default.
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- W2410548530 date "1992-01-01" @default.
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- W2410548530 title "[Comparative analysis of mezlocillin/metronidazole and amoxicillin/clavulanic acid as one shot preventive antibiotic administration in colorectal interventions]." @default.
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