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- W2410550785 abstract "The influence on the duration of CR and survival of 2 modalities (MTX + hydrocortisone IT, with and without TCT) for the prevention of meningeal CNS involvement was assessed in 24 children with acute lymphoblastic leukemia. Of the 9 subjects who received MTX and hydrocortisone only, 42% were still in CR 33 months after its attainment, as opposed to 75% of the 15 who also received TCT. Survival at 33 months after diagnosis was 89% and 82% in the 2 groups. The results are compared with those obtained in an earlier series of 14 children who received no prophylactic treatment. Here CR at 45 months was 25% and survival 46%. Eight subjects died, as opposed to 3 (1 in CR) in the present series." @default.
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- W2410550785 date "1977-07-01" @default.
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- W2410550785 title "Prevention of Meningeal CNS Involvement as a Factor Influencing the Duration of Complete Remission and Survival in Childhood Acute Lymphoblastic Leukemia" @default.
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- W2410550785 doi "https://doi.org/10.1177/030089167706300408" @default.
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