Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410553783> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2410553783 endingPage "9" @default.
- W2410553783 startingPage "615" @default.
- W2410553783 abstract "Meningitis caused by Gram-negative bacilli creates difficult problems since most strains are multiresistant. The purpose of this study was to evaluate the effectiveness of lamoxactam administered intravenously. Eleven patients admitted to an intensive care unit with meningitis due to Gram-negative bacilli were treated with this antibiotic, administered alone in 9 cases. Three patients had ventriculitis. Eight survived. The MICs ranged from 0.06 to 0.5 microgram/ml in 10 cases. The CSF was sterilized and rapidly became normal. Meningeal concentrations varied from 1-5 to 62 micrograms/ml and the CSF was bactericidal. In one female patient the CSF was sterile on the 5th day of treatment but remained abnormal; the meningeal concentration of lamoxactam (35 micrograms/ml) was much higher than the MIC (2 micrograms/ml) but below the MBC (128 micrograms/ml), which was consistent with the absence of bactericidal effect of the CSF. Owing to its very low CMIs and satisfactory passage through the blood-brain barrier, lamoxactam administered alone can be successful in the treatment of Gram-negative meningitis and ventriculitis. However, the bactericidal effect of the CSF should be rapidly assessed." @default.
- W2410553783 created "2016-06-24" @default.
- W2410553783 creator A5035212508 @default.
- W2410553783 creator A5049327143 @default.
- W2410553783 creator A5054714190 @default.
- W2410553783 creator A5064814437 @default.
- W2410553783 creator A5066853452 @default.
- W2410553783 creator A5089731910 @default.
- W2410553783 date "1983-03-05" @default.
- W2410553783 modified "2023-10-14" @default.
- W2410553783 title "[Treatment of enterobacterial meningitis in adults with intravenous lamoxactam]." @default.
- W2410553783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6220282" @default.
- W2410553783 hasPublicationYear "1983" @default.
- W2410553783 type Work @default.
- W2410553783 sameAs 2410553783 @default.
- W2410553783 citedByCount "4" @default.
- W2410553783 crossrefType "journal-article" @default.
- W2410553783 hasAuthorship W2410553783A5035212508 @default.
- W2410553783 hasAuthorship W2410553783A5049327143 @default.
- W2410553783 hasAuthorship W2410553783A5054714190 @default.
- W2410553783 hasAuthorship W2410553783A5064814437 @default.
- W2410553783 hasAuthorship W2410553783A5066853452 @default.
- W2410553783 hasAuthorship W2410553783A5089731910 @default.
- W2410553783 hasConcept C126322002 @default.
- W2410553783 hasConcept C141071460 @default.
- W2410553783 hasConcept C176947019 @default.
- W2410553783 hasConcept C202751555 @default.
- W2410553783 hasConcept C26381139 @default.
- W2410553783 hasConcept C2776870249 @default.
- W2410553783 hasConcept C2779651940 @default.
- W2410553783 hasConcept C2779862588 @default.
- W2410553783 hasConcept C2781026528 @default.
- W2410553783 hasConcept C42219234 @default.
- W2410553783 hasConcept C501593827 @default.
- W2410553783 hasConcept C51296783 @default.
- W2410553783 hasConcept C523546767 @default.
- W2410553783 hasConcept C54355233 @default.
- W2410553783 hasConcept C55493867 @default.
- W2410553783 hasConcept C71924100 @default.
- W2410553783 hasConcept C86803240 @default.
- W2410553783 hasConcept C89423630 @default.
- W2410553783 hasConceptScore W2410553783C126322002 @default.
- W2410553783 hasConceptScore W2410553783C141071460 @default.
- W2410553783 hasConceptScore W2410553783C176947019 @default.
- W2410553783 hasConceptScore W2410553783C202751555 @default.
- W2410553783 hasConceptScore W2410553783C26381139 @default.
- W2410553783 hasConceptScore W2410553783C2776870249 @default.
- W2410553783 hasConceptScore W2410553783C2779651940 @default.
- W2410553783 hasConceptScore W2410553783C2779862588 @default.
- W2410553783 hasConceptScore W2410553783C2781026528 @default.
- W2410553783 hasConceptScore W2410553783C42219234 @default.
- W2410553783 hasConceptScore W2410553783C501593827 @default.
- W2410553783 hasConceptScore W2410553783C51296783 @default.
- W2410553783 hasConceptScore W2410553783C523546767 @default.
- W2410553783 hasConceptScore W2410553783C54355233 @default.
- W2410553783 hasConceptScore W2410553783C55493867 @default.
- W2410553783 hasConceptScore W2410553783C71924100 @default.
- W2410553783 hasConceptScore W2410553783C86803240 @default.
- W2410553783 hasConceptScore W2410553783C89423630 @default.
- W2410553783 hasIssue "10" @default.
- W2410553783 hasLocation W24105537831 @default.
- W2410553783 hasOpenAccess W2410553783 @default.
- W2410553783 hasPrimaryLocation W24105537831 @default.
- W2410553783 hasRelatedWork W1995515116 @default.
- W2410553783 hasRelatedWork W1997845067 @default.
- W2410553783 hasRelatedWork W1999699630 @default.
- W2410553783 hasRelatedWork W2025070614 @default.
- W2410553783 hasRelatedWork W2034378640 @default.
- W2410553783 hasRelatedWork W2086918339 @default.
- W2410553783 hasRelatedWork W2152114466 @default.
- W2410553783 hasRelatedWork W2410553783 @default.
- W2410553783 hasRelatedWork W2470914114 @default.
- W2410553783 hasRelatedWork W43405978 @default.
- W2410553783 hasVolume "12" @default.
- W2410553783 isParatext "false" @default.
- W2410553783 isRetracted "false" @default.
- W2410553783 magId "2410553783" @default.
- W2410553783 workType "article" @default.