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- W2410623717 abstract "Abrupt withdrawal jumping behavior in morphine-dependent mice is accompanied by a decrease in brain dopamine turnover and an increase in brain dopamine level which parallel strain differences in jumping incidence. Both naloxone-precipitated and abrupt withdrawal jumping behavior are inhibited in a dose-dependent manner by the dopaminergic agonist apomorphine. A cataleptic dose of the dopaminergic antagonist, haloperidol, does not block naloxone-precipitated jumping, but does significantly block the inhibition by apomorphine. These findings indicate that there may be a decrease release of dopamine in the brain during the expression of withdrawal jumping behavior and that dopaminergic activation may be inhibitory to this behavior." @default.
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- W2410623717 date "1976-11-01" @default.
- W2410623717 modified "2023-09-23" @default.
- W2410623717 title "Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice." @default.
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