FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2410713200> ?p ?o ?g. }

• W2410713200 endingPage "7" @default.
• W2410713200 startingPage "I60" @default.
• W2410713200 abstract "To assess the effect of temperature, oxygenated blood and crystalloid cardioplegic solutions (CPs) at infusion temperatures of 20 degrees C, 10 degrees C and 4 degrees C were compared. The amount of potassium in each CP was 25 mEq/l. There were six study groups with seven canine hearts in each group, all of which were subjected to 90 minutes of global ischemia at 20 degrees C, 10 degrees C or 4 degrees C, followed by 45 minutes of normothermic reperfusion. During ischemia, either blood or crystalloid CP was given every 30 minutes. With each infusion, any change in myocardial oxygen tension was recorded using mass spectrometry, and oxygen consumption (MVO2) was calculated. Left ventricular (LV) function was assessed before and after ischemia in all hearts by measuring isovolumic developed pressure using an intraventricular balloon. Injection of 20 degrees C blood CP resulted in a mean increase in intramyocardial oxygen tension (PO2) of 7 mm Hg. At 10 degrees C or 4 degrees C, blood CP infusions did not cause a significant increase in intramyocardial PO2, while with crystalloid CP, intramyocardial PO2 did not increase at any of the three infusion temperatures. The mean MVO2 with each blood CP injection, expressed as ml O2/100 g LV wet weight, was 16.5 +/- 0.8 for 20 degrees C blood, 4.1 +/- 0.3 for 10 degrees C blood and 3.5 +/- 0.4 for 4 degrees C blood (p less than 0.001, 20 degrees C blood vs 10 degrees C and 4 degrees C blood). MVO2 with each crystalloid CP injection was 0.9 +/- 0.1 for 20 degrees C CP, 0.8 +/- 0.1 for 10 degrees C CP, and 0.7 +/- 0.1 for 4 degrees C CP. Recovery of developed pressure after 45 minutes of reperfusion, expressed as a percentage of preischemic control, was 76.0 +/- 3.4% or 20 degrees C blood CP, 65.6 +/- 2.3% for 10 degrees C blood CP, and 54.0 +/- 2.7% for 4 degrees C blood CP (p less than 0.05, 20 degrees C blood CP vs 10 degrees C and 4 degrees C blood CP). Recovery of developed pressure, also expressed as a percentage of preischemic control, was 56.6 +/- 1.4% for 20 degrees C crystalloid CP, 72.9 +/- 3.0% for 10 degrees C crystalloid CP, and 72.0 +/- 2.3% for 4 degrees C crystalloid CP (p less than 0.05, 20 degrees C crystalloid CP vs 10 degrees C and 4 degrees C crystalloid CP). These data show that blood CP is most effective when infused at 20 degrees C. The use of 10 degrees C blood CP enhanced myocardial cooling, but was of no additional benefit, presumably because there was little oxygen delivery. Blood CP at 4 degrees C resulted in significantly poorer preservation of LV function. Crystalloid CP infused at either 4 degrees C or 10 degrees C was as effective as 20 degrees C blood CP, despite the absence of oxygen use by hearts treated with crystalloid CP." @default.
• W2410713200 created "2016-06-24" @default.
• W2410713200 creator A5012503017 @default.
• W2410713200 creator A5019483165 @default.
• W2410713200 creator A5056320703 @default.
• W2410713200 creator A5074277336 @default.
• W2410713200 creator A5085683791 @default.
• W2410713200 date "1982-08-01" @default.
• W2410713200 modified "2023-09-23" @default.
• W2410713200 title "Failure of blood cardioplegia to protect myocardium at lower temperatures." @default.
• W2410713200 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6805979" @default.
• W2410713200 hasPublicationYear "1982" @default.
• W2410713200 type Work @default.
• W2410713200 sameAs 2410713200 @default.
• W2410713200 citedByCount "38" @default.
• W2410713200 countsByYear W24107132002015 @default.
• W2410713200 crossrefType "journal-article" @default.
• W2410713200 hasAuthorship W2410713200A5012503017 @default.
• W2410713200 hasAuthorship W2410713200A5019483165 @default.
• W2410713200 hasAuthorship W2410713200A5056320703 @default.
• W2410713200 hasAuthorship W2410713200A5074277336 @default.
• W2410713200 hasAuthorship W2410713200A5085683791 @default.
• W2410713200 hasConcept C126322002 @default.
• W2410713200 hasConcept C164705383 @default.
• W2410713200 hasConcept C178790620 @default.
• W2410713200 hasConcept C185592680 @default.
• W2410713200 hasConcept C2993207723 @default.
• W2410713200 hasConcept C42219234 @default.
• W2410713200 hasConcept C540031477 @default.
• W2410713200 hasConcept C541997718 @default.
• W2410713200 hasConcept C71924100 @default.
• W2410713200 hasConcept C84393581 @default.
• W2410713200 hasConceptScore W2410713200C126322002 @default.
• W2410713200 hasConceptScore W2410713200C164705383 @default.
• W2410713200 hasConceptScore W2410713200C178790620 @default.
• W2410713200 hasConceptScore W2410713200C185592680 @default.
• W2410713200 hasConceptScore W2410713200C2993207723 @default.
• W2410713200 hasConceptScore W2410713200C42219234 @default.
• W2410713200 hasConceptScore W2410713200C540031477 @default.
• W2410713200 hasConceptScore W2410713200C541997718 @default.
• W2410713200 hasConceptScore W2410713200C71924100 @default.
• W2410713200 hasConceptScore W2410713200C84393581 @default.
• W2410713200 hasIssue "2 Pt 2" @default.
• W2410713200 hasLocation W24107132001 @default.
• W2410713200 hasOpenAccess W2410713200 @default.
• W2410713200 hasPrimaryLocation W24107132001 @default.
• W2410713200 hasRelatedWork W1979703506 @default.
• W2410713200 hasRelatedWork W2019086812 @default.
• W2410713200 hasRelatedWork W2019471644 @default.
• W2410713200 hasRelatedWork W2046241909 @default.
• W2410713200 hasRelatedWork W2052580913 @default.
• W2410713200 hasRelatedWork W2322900513 @default.
• W2410713200 hasRelatedWork W2394579735 @default.
• W2410713200 hasRelatedWork W2400974039 @default.
• W2410713200 hasRelatedWork W2440686219 @default.
• W2410713200 hasRelatedWork W3141700921 @default.
• W2410713200 hasVolume "66" @default.
• W2410713200 isParatext "false" @default.
• W2410713200 isRetracted "false" @default.
• W2410713200 magId "2410713200" @default.
• W2410713200 workType "article" @default.