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• W2410795579 abstract "Amac: Perkutan yolla sol atriyal apandisin (SAA) kapatilmasi atriyal fibrilasyonlu (AF) hastalarda, ozellikle de oral antikoagulasyon tedavisine kontrendikasyonu olanlarda, tromboembolik inmenin onlenmesinde onemli bir tedavi secenegidir. Bu calismada, SAA’nin perkutan yolla, WATCHMAN SAA sistemiyle kapatildigi (ilk deneyimlerimiz) olgularda kisa donem sonuclar degerlendirildi. Calisma plani: Kapak disi nedenli AF olan, kardiyoembolik inme gelismesi acisindan yuksek riskli (ort. CHADS2 skoru 2.6±1.2, ort. CHA2DS2-VASc skoru 4.0±1.5) ve oral antikoagulasyon tedavisi icin kontrendikasyon bulunan 11 hastaya (8 erkek, 3 kadin; ort. yas 68.4±7.0) WATCHMAN SAA sistemiyle perkutan SAA kapatma uygulandi. Islemler genel anestezi altinda, floroskopi ve transozofageal ekokardiyografi (TOE) kilavuzlugunda yapildi. Hastalar klinik olarak (45. gun ve 6. ayda) ve TOE (45. gunde) ile degerlendirildi. Bulgular: Tum hastalarda (%100) SAA basarili sekilde kapatildi. Ortalama islem suresi 58.6±8.1 dk, ortalama floroskopi suresi 19.1±5.2 dk idi. Transozofageal ekokardiyografi ile ortalama SAA ostiyum capi 20.4±3.8 mm olculdu. Yerlestirilen cihazlarin ortalama boyutu 24.6±3.8 mm idi. Islem sonrasi hastanede yatis suresi ortalama 1.7±0.9 gundu. Kontrol TOE’de SAA’nin cihazla iliskili trombus olusmadan kapandigi gozlendi. Iki hastada (%18.2) cihaz cevresinde hafif kacak (<3 mm) vardi. Izlem suresince (ortanca 90 gun, ceyreklerarasi aralik 60-185 gun) hicbir hastada onemli istenmeyen olay izlenmedi. Sonuc: WATCHMAN SAA sistemi ile perkutan SAA kapatilmasindaki ilk deneyimlerimiz bu yontemin guvenli ve uygulanabilir, kisa donem sonuclarinin olumlu oldugunu gostermektedir. Objectives: Percutaneous left atrial appendage (LAA) closure is an important therapeutic option for prevention of thromboembolic stroke in patients with atrial fibrillation (AF), especially when contraindications exist for oral anticoagulation. We aimed to evaluate our shortterm results of LAA closure (initial experience) using the WATCHMAN LAA system. Study design: Eleven patients (8 men, 3 women; mean age 68.4±7.0 years) with nonvalvular AF, a high risk for cardioembolic stroke (mean CHADS2 score 2.6±1.2, mean CHA2DS2-VASc score 4.0±1.5), and contraindications to oral anticoagulation underwent percutaneous LAA closure using the WATCHMAN LAA system. All the procedures were performed under general anesthesia and fluoroscopy and transesophageal echocardiography (TEE) guidance. The patients were evaluated clinically (at 45 days and 6 months) and by TEE (at 45 days). Results: The LAA was successfully occluded in all the patients (100%). The mean procedural and fluoroscopy times were 58.6±8.1 and 19.1±5.2 minutes, respectively. The mean diameter of the LAA ostium was measured as 20.4±3.8 mm by TEE. The mean device size was 24.6±3.8 mm. The mean hospital stay was 1.7±0.9 days. Follow-up TEE showed closure of all LAA orifices without device-related thrombus formation. Two patients (18.2%) had minimal peri-device leaks (<3 mm). None of the patients experienced major adverse events during a median follow-up of 90 days (interquartile range 60-185 days). Conclusion: Our initial experience suggests that percutaneous LAA closure with the WATCHMAN LAA system is safe and feasible, with favorable short-term clinical outcomes. OZET ABSTRACT" @default.
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• W2410795579 date "2012-03-01" @default.
• W2410795579 modified "2023-10-16" @default.
• W2410795579 title "OP-114 PERCUTANEOUS CLOSURE OF THE LEFT ATRIAL APPENDAGE: A NEW OPTION FOR THE PREVENTION OF THROMBOEMBOLIC STROKE" @default.
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• W2410795579 doi "https://doi.org/10.1016/s0167-5273(12)70061-x" @default.
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