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- W2410982809 abstract "Abstract Background Urinary tract infections (UTI) are one of the most common bacterial infections in children and a major cause of hospitalization. In this study we investigated the clinical characteristics, causative uropathogens; their antibiotic susceptibility and resistance patterns, treatment modalities and efficacy in children hospitalized for UTI in a tertiary care setting. Methods Patients hospitalized for an upper UTI between March 2009 and July 2014 were enrolled. The urine culture–antibiogram results and accompanying urinary tract abnormalities were recorded retrospectively. Results A total of 142 patients (104 girls, 73.2%; 38 boys, 26.8%) were enrolled. Mean patient age was 32.6 ± 4.1 months. History of recurrent UTI was present in 45.8% (n = 65), with prior hospitalization in 12.0% (n = 17). Frequency of vesicoureteral reflux was 18.3% (n = 26). Gram‐negative enteric microorganisms yielded growth in all culture‐positive UTI and the most common microorganism was Escherichia coli (n = 114, 80.3%). Extended spectrum beta‐lactamase‐producing (ESBL (+)) bacterial strains were detected in 49.3% (n = 70), with third‐generation cephalosporin resistance in all and increased duration of hospitalization. Conclusions The prevalence of UTI with ESBL (+) bacterial strains with multi‐drug resistance is increasing in the hospitalized pediatric population, therefore rational use of antibiotics is essential." @default.
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- W2410982809 date "2016-02-03" @default.
- W2410982809 modified "2023-10-15" @default.
- W2410982809 title "Causative pathogens and antibiotic resistance in children hospitalized for urinary tract infection" @default.
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- W2410982809 doi "https://doi.org/10.1111/ped.12842" @default.
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