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- W2411324069 abstract "In Chaps. 2 and 3, we discuss the methods for calculating the sample size required to design a trial with multiple co-primary endpoints. These methods require considerable mathematical sophistication and knowledge of programming techniques, effectively limiting their application in practice. To increase the practicality of these methods, in this chapter we provide an efficient algorithm for calculating the sample size and present a convenient sample size formula with associated numerical tables for sizing clinical trials with multiple co-primary endpoints. We provide numerical examples to illustrate use of the formula and associated tables, and provide the programming codes for the R and SAS software packages." @default.
- W2411324069 created "2016-06-24" @default.
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- W2411324069 date "2015-01-01" @default.
- W2411324069 modified "2023-09-24" @default.
- W2411324069 title "Convenient Sample Size Formula" @default.
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- W2411324069 doi "https://doi.org/10.1007/978-3-319-22005-5_4" @default.
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