FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2411347060> ?p ?o ?g. }

• W2411347060 endingPage "7984" @default.
• W2411347060 startingPage "7969" @default.
• W2411347060 abstract "Spatial resolution of clinical PET scanners is limited by detector design and photon non-colinearity. Although dedicated small animal PET scanners using specialized high-resolution detectors have been developed, enhancing the spatial resolution of clinical PET scanners is of interest as a more available alternative. Multi-pinhole 511 keV SPECT is capable of high spatial resolution but requires heavily shielded collimators to avoid significant background counts. A practical approach with clinical PET detectors is to combine multi-pinhole collimation with coincidence detection. In this new hybrid modality, there are three locations associated with each event, namely those of the two detected photons and the pinhole aperture. These three locations over-determine the line of response and provide redundant information that is superior to coincidence detection or pinhole collimation alone. Multi-pinhole collimation provides high resolution and avoids non-colinearity error but is subject to collimator penetration and artifacts from overlapping projections. However the coincidence information, though at lower resolution, is valuable for determining whether the photon passed near a pinhole within the cone acceptance angle and for identifying through which pinhole the photon passed. This information allows most photons penetrating through the collimator to be rejected and avoids overlapping projections. With much improved event rejection, a collimator with minimal shielding may be used, and a lightweight add-on collimator for high resolution imaging is feasible for use with a clinical PET scanner. Monte Carlo simulations were performed of a (18)F hot rods phantom and a 54-pinhole unfocused whole-body mouse collimator with a clinical PET scanner. Based on coincidence information and pinhole geometry, events were accepted or rejected, and pinhole-specific crystal-map projections were generated. Tomographic images then were reconstructed using a conventional pinhole SPECT algorithm. Hot rods of 1.4 mm diameter were resolved easily in a simulated phantom. System sensitivity was 0.09% for a simulated 70-mm line source corresponding to the NEMA NU-4 mouse phantom. Higher resolution is expected with further optimization of pinhole design, and higher sensitivity is expected with a focused and denser pinhole configuration. The simulations demonstrate high spatial resolution and feasibility of small animal imaging with an add-on multi-pinhole collimator for a clinical PET scanner. Further work is needed to develop geometric calibration and quantitative data corrections and, eventually, to construct a prototype device and produce images with physical phantoms." @default.
• W2411347060 created "2016-06-24" @default.
• W2411347060 creator A5034482985 @default.
• W2411347060 date "2015-09-29" @default.
• W2411347060 modified "2023-09-27" @default.
• W2411347060 title "Enhanced PET resolution by combining pinhole collimation and coincidence detection" @default.
• W2411347060 cites W1602402196 @default.
• W2411347060 cites W1972395730 @default.
• W2411347060 cites W1979383935 @default.
• W2411347060 cites W1986532691 @default.
• W2411347060 cites W2004960073 @default.
• W2411347060 cites W2005318992 @default.
• W2411347060 cites W2032874357 @default.
• W2411347060 cites W2039515505 @default.
• W2411347060 cites W2044250041 @default.
• W2411347060 cites W2055899745 @default.
• W2411347060 cites W2069437309 @default.
• W2411347060 cites W2070398860 @default.
• W2411347060 cites W2070691463 @default.
• W2411347060 cites W2075734152 @default.
• W2411347060 cites W2079254084 @default.
• W2411347060 cites W2082732984 @default.
• W2411347060 cites W2093162406 @default.
• W2411347060 cites W2100835922 @default.
• W2411347060 cites W2108145991 @default.
• W2411347060 cites W2111249617 @default.
• W2411347060 cites W2126842988 @default.
• W2411347060 cites W2127104394 @default.
• W2411347060 cites W2127144183 @default.
• W2411347060 cites W2128158076 @default.
• W2411347060 cites W2128768934 @default.
• W2411347060 cites W2140445473 @default.
• W2411347060 cites W2144240099 @default.
• W2411347060 cites W2146006128 @default.
• W2411347060 cites W2154744699 @default.
• W2411347060 cites W2155263430 @default.
• W2411347060 cites W2155830585 @default.
• W2411347060 cites W2171362005 @default.
• W2411347060 cites W2177428623 @default.
• W2411347060 cites W2534354170 @default.
• W2411347060 cites W2539435447 @default.
• W2411347060 cites W2539682833 @default.
• W2411347060 cites W2544649344 @default.
• W2411347060 cites W3023367790 @default.
• W2411347060 doi "https://doi.org/10.1088/0031-9155/60/20/7969" @default.
• W2411347060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26418305" @default.
• W2411347060 hasPublicationYear "2015" @default.
• W2411347060 type Work @default.
• W2411347060 sameAs 2411347060 @default.
• W2411347060 citedByCount "5" @default.
• W2411347060 countsByYear W24113470602017 @default.
• W2411347060 countsByYear W24113470602018 @default.
• W2411347060 countsByYear W24113470602020 @default.
• W2411347060 countsByYear W24113470602023 @default.
• W2411347060 crossrefType "journal-article" @default.
• W2411347060 hasAuthorship W2411347060A5034482985 @default.
• W2411347060 hasConcept C104293457 @default.
• W2411347060 hasConcept C120665830 @default.
• W2411347060 hasConcept C121332964 @default.
• W2411347060 hasConcept C138268822 @default.
• W2411347060 hasConcept C142724271 @default.
• W2411347060 hasConcept C154945302 @default.
• W2411347060 hasConcept C159317903 @default.
• W2411347060 hasConcept C19527891 @default.
• W2411347060 hasConcept C204787440 @default.
• W2411347060 hasConcept C205372480 @default.
• W2411347060 hasConcept C2776700484 @default.
• W2411347060 hasConcept C2779200277 @default.
• W2411347060 hasConcept C2779832538 @default.
• W2411347060 hasConcept C34445779 @default.
• W2411347060 hasConcept C41008148 @default.
• W2411347060 hasConcept C520434653 @default.
• W2411347060 hasConcept C71924100 @default.
• W2411347060 hasConcept C94915269 @default.
• W2411347060 hasConceptScore W2411347060C104293457 @default.
• W2411347060 hasConceptScore W2411347060C120665830 @default.
• W2411347060 hasConceptScore W2411347060C121332964 @default.
• W2411347060 hasConceptScore W2411347060C138268822 @default.
• W2411347060 hasConceptScore W2411347060C142724271 @default.
• W2411347060 hasConceptScore W2411347060C154945302 @default.
• W2411347060 hasConceptScore W2411347060C159317903 @default.
• W2411347060 hasConceptScore W2411347060C19527891 @default.
• W2411347060 hasConceptScore W2411347060C204787440 @default.
• W2411347060 hasConceptScore W2411347060C205372480 @default.
• W2411347060 hasConceptScore W2411347060C2776700484 @default.
• W2411347060 hasConceptScore W2411347060C2779200277 @default.
• W2411347060 hasConceptScore W2411347060C2779832538 @default.
• W2411347060 hasConceptScore W2411347060C34445779 @default.
• W2411347060 hasConceptScore W2411347060C41008148 @default.
• W2411347060 hasConceptScore W2411347060C520434653 @default.
• W2411347060 hasConceptScore W2411347060C71924100 @default.
• W2411347060 hasConceptScore W2411347060C94915269 @default.
• W2411347060 hasIssue "20" @default.
• W2411347060 hasLocation W24113470601 @default.
• W2411347060 hasLocation W24113470602 @default.
• W2411347060 hasOpenAccess W2411347060 @default.
• W2411347060 hasPrimaryLocation W24113470601 @default.
• W2411347060 hasRelatedWork W1606383816 @default.

• next