Matches in SemOpenAlex for { <https://semopenalex.org/work/W2411636191> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2411636191 endingPage "39" @default.
- W2411636191 startingPage "30" @default.
- W2411636191 abstract "In the article the results of the long-term researches revealing the essence of the following three phenomena are generalized. 1. Participation of active oxygen species (especially, superoxide radical) in activation of zymogens--plasminogen, trypsinogen, chymotrypsinogen, pepsinogen and in realization of the catalytic (proteolytic) function of a number of proteinases. The essence of the hypothesis of oxygen-dependent reactions of proteolysis is stated. As shown by the example of mouse brain homogenate fractions, the plasminogen-activating ability of the fractions can also be realized via this way. From the positions of these views the experimental facts obtained about the influence of streptokinase and plasminogen on vital activity of nervous tissue cells are analysed. 2. Suppression of proteolytic reactions by ATP: plasminogen-activating ability of streptokinase, gamma- and betasubunits of the nerve growth factor, proteolytic activity of Arthrobothrys longa proteinases, destroyed cells of Corynebacterium diphtheriae PW-8. In some cases a significant was reached at concentration of ATP < or = 0.001 M. The depends on protein substrates used. 3. The increase of fibrinolytic activity of the mitochondrial fraction of the mouse brain and liver, proteolytic activity of human lymphoblasts of transplanted lines in the presence of inorganic orthophosphate. Judging by the results of inhibitory analysis, it is not caused by the resynthesis of ATP in the system and has an independent character--phosphate effect in proteolysis. 4. The results of our researches of formation of stable equimolar complexes of streptokinase or plasminogen with enzymes of carbohydrate-energetic metabolism are briefly analysed. The results of researches of functional properties of the molecules of diphtheria toxin, the nerve growth factor and it subunits are summarized. A number of fundamental and applied consequences of these phenomena are considered." @default.
- W2411636191 created "2016-06-24" @default.
- W2411636191 creator A5045675437 @default.
- W2411636191 creator A5048857925 @default.
- W2411636191 date "2006-12-31" @default.
- W2411636191 modified "2023-09-23" @default.
- W2411636191 title "Some unusual manifestations of proteolysis." @default.
- W2411636191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17543196" @default.
- W2411636191 hasPublicationYear "2006" @default.
- W2411636191 type Work @default.
- W2411636191 sameAs 2411636191 @default.
- W2411636191 citedByCount "0" @default.
- W2411636191 crossrefType "journal-article" @default.
- W2411636191 hasAuthorship W2411636191A5045675437 @default.
- W2411636191 hasAuthorship W2411636191A5048857925 @default.
- W2411636191 hasConcept C126322002 @default.
- W2411636191 hasConcept C181199279 @default.
- W2411636191 hasConcept C185592680 @default.
- W2411636191 hasConcept C2776336681 @default.
- W2411636191 hasConcept C2781071845 @default.
- W2411636191 hasConcept C2781307694 @default.
- W2411636191 hasConcept C3019223276 @default.
- W2411636191 hasConcept C500558357 @default.
- W2411636191 hasConcept C55493867 @default.
- W2411636191 hasConcept C71924100 @default.
- W2411636191 hasConcept C86803240 @default.
- W2411636191 hasConceptScore W2411636191C126322002 @default.
- W2411636191 hasConceptScore W2411636191C181199279 @default.
- W2411636191 hasConceptScore W2411636191C185592680 @default.
- W2411636191 hasConceptScore W2411636191C2776336681 @default.
- W2411636191 hasConceptScore W2411636191C2781071845 @default.
- W2411636191 hasConceptScore W2411636191C2781307694 @default.
- W2411636191 hasConceptScore W2411636191C3019223276 @default.
- W2411636191 hasConceptScore W2411636191C500558357 @default.
- W2411636191 hasConceptScore W2411636191C55493867 @default.
- W2411636191 hasConceptScore W2411636191C71924100 @default.
- W2411636191 hasConceptScore W2411636191C86803240 @default.
- W2411636191 hasIssue "4" @default.
- W2411636191 hasLocation W24116361911 @default.
- W2411636191 hasLocation W24116361912 @default.
- W2411636191 hasOpenAccess W2411636191 @default.
- W2411636191 hasPrimaryLocation W24116361911 @default.
- W2411636191 hasRelatedWork W1531318383 @default.
- W2411636191 hasRelatedWork W180742456 @default.
- W2411636191 hasRelatedWork W1977745385 @default.
- W2411636191 hasRelatedWork W1981062761 @default.
- W2411636191 hasRelatedWork W1981525816 @default.
- W2411636191 hasRelatedWork W1988222400 @default.
- W2411636191 hasRelatedWork W1993908118 @default.
- W2411636191 hasRelatedWork W1997793089 @default.
- W2411636191 hasRelatedWork W2001940949 @default.
- W2411636191 hasRelatedWork W2018988680 @default.
- W2411636191 hasRelatedWork W2021957090 @default.
- W2411636191 hasRelatedWork W2023339576 @default.
- W2411636191 hasRelatedWork W2027765746 @default.
- W2411636191 hasRelatedWork W2154584639 @default.
- W2411636191 hasRelatedWork W231131013 @default.
- W2411636191 hasRelatedWork W2396546002 @default.
- W2411636191 hasRelatedWork W2405924462 @default.
- W2411636191 hasRelatedWork W2410513440 @default.
- W2411636191 hasRelatedWork W2419170107 @default.
- W2411636191 hasRelatedWork W38941340 @default.
- W2411636191 hasVolume "52" @default.
- W2411636191 isParatext "false" @default.
- W2411636191 isRetracted "false" @default.
- W2411636191 magId "2411636191" @default.
- W2411636191 workType "article" @default.