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- W2411957773 abstract "Sharp and coworkers (69) recently described a group of patients with over-lapping syndromes of lupus erythematosus, polymyositis and progressive systemic sclerosis. Since all these patients showed high titers of an antibody against RNP (ribonucleoproutein), a saline extractable constituent of nuclei, the disease was supposed to be a unique entity within the spectrum of collagen diseases (mixed connective tissue disease, overlapping syndrome). The nosological entity, however, remains to be further established since RNP-antibodies not infrequently occur in other collagenoses (LE, RA) and transition of MCTD in LE have been reported. The clinical syndromes and the serological features of MCTD are described." @default.
- W2411957773 created "2016-06-24" @default.
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- W2411957773 date "1981-11-01" @default.
- W2411957773 modified "2023-09-23" @default.
- W2411957773 title "[The Sharp syndrome (mixed connective tissue diseases) (author's transl)]." @default.
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