FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2412272167> ?p ?o ?g. }

• W2412272167 endingPage "67" @default.
• W2412272167 startingPage "10657" @default.
• W2412272167 abstract "Neurotrophin receptor-mediated melanoma antigen-encoding gene homology (NRAGE) is an important regulator of proliferation, cell cycle arrest and apoptosis. Our previous study showed that NRAGE is an important regulator of proliferation and odontogenic differentiation of mouse dental pulp cells. This study aimed to investigate the effects of NRAGE on the cell cycle and apoptosis on human dental pulp cells (hDPCs) and MDPC-23.Cells were infected by recombinant lentivirus to stably knockdown the expression of NRAGE, then the biological effects of NRAGE on the MDPC-23 was detected. The cell cycle distributions and apoptosis of hDPCs and MCPC-23 were performed by flow cytometric analysis. Simultaneously, the cell cycle and apoptosis were also detected after cells treated with IKK inhibitor.The mRNA and protein levels of NRAGE decreased significantly after infected by recombinant lentivirus. Knockdown of NRAGE inhibited the apoptosis in hDPCs and MCPC-23. Knockdown of NRAGE show significantly G0G1 arrest in hDPCs, while no significantly difference in MDPC-23. Meanwhile, Knockdown of NRAGE activated the NF-κB signaling pathway. After treated with IKK inhibitor, the effect of NRAGE knockdown on apoptosis was reversed in both hDPCs and MDPC-23.NRAGE is a potent regulator for cell cycle and apoptosis of hDPCs. Knockdown of NRAGE inhibited apoptosis of hDPCs and MDPC-23 through the NF-κB signaling pathway." @default.
• W2412272167 created "2016-06-24" @default.
• W2412272167 creator A5012677271 @default.
• W2412272167 creator A5025727346 @default.
• W2412272167 creator A5030007770 @default.
• W2412272167 creator A5032712128 @default.
• W2412272167 creator A5044619625 @default.
• W2412272167 creator A5046855922 @default.
• W2412272167 creator A5048164279 @default.
• W2412272167 creator A5048379858 @default.
• W2412272167 creator A5081954344 @default.
• W2412272167 creator A5088793746 @default.
• W2412272167 date "2015-01-01" @default.
• W2412272167 modified "2023-09-27" @default.
• W2412272167 title "The Effect of NRAGE on cell cycle and apoptosis of human dental pulp cells and MDPC-23." @default.
• W2412272167 cites W158576505 @default.
• W2412272167 cites W1966923590 @default.
• W2412272167 cites W1971212650 @default.
• W2412272167 cites W1974725392 @default.
• W2412272167 cites W1991745061 @default.
• W2412272167 cites W2008187512 @default.
• W2412272167 cites W2014043099 @default.
• W2412272167 cites W2017528608 @default.
• W2412272167 cites W2018258194 @default.
• W2412272167 cites W2023123039 @default.
• W2412272167 cites W2033927170 @default.
• W2412272167 cites W2039818183 @default.
• W2412272167 cites W2042571684 @default.
• W2412272167 cites W2049391776 @default.
• W2412272167 cites W2053278893 @default.
• W2412272167 cites W2053881507 @default.
• W2412272167 cites W2055782345 @default.
• W2412272167 cites W2056553180 @default.
• W2412272167 cites W2062950682 @default.
• W2412272167 cites W2063748998 @default.
• W2412272167 cites W2092916187 @default.
• W2412272167 cites W2095618486 @default.
• W2412272167 cites W2096739766 @default.
• W2412272167 cites W2113596764 @default.
• W2412272167 cites W2116978350 @default.
• W2412272167 cites W2130155165 @default.
• W2412272167 cites W2135651311 @default.
• W2412272167 cites W2143113229 @default.
• W2412272167 cites W2145040826 @default.
• W2412272167 cites W2146913154 @default.
• W2412272167 cites W2153781529 @default.
• W2412272167 cites W2154423739 @default.
• W2412272167 cites W2161447467 @default.
• W2412272167 cites W2164280040 @default.
• W2412272167 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4565240" @default.
• W2412272167 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26379857" @default.
• W2412272167 hasPublicationYear "2015" @default.
• W2412272167 type Work @default.
• W2412272167 sameAs 2412272167 @default.
• W2412272167 citedByCount "1" @default.
• W2412272167 countsByYear W24122721672016 @default.
• W2412272167 crossrefType "journal-article" @default.
• W2412272167 hasAuthorship W2412272167A5012677271 @default.
• W2412272167 hasAuthorship W2412272167A5025727346 @default.
• W2412272167 hasAuthorship W2412272167A5030007770 @default.
• W2412272167 hasAuthorship W2412272167A5032712128 @default.
• W2412272167 hasAuthorship W2412272167A5044619625 @default.
• W2412272167 hasAuthorship W2412272167A5046855922 @default.
• W2412272167 hasAuthorship W2412272167A5048164279 @default.
• W2412272167 hasAuthorship W2412272167A5048379858 @default.
• W2412272167 hasAuthorship W2412272167A5081954344 @default.
• W2412272167 hasAuthorship W2412272167A5088793746 @default.
• W2412272167 hasConcept C104317684 @default.
• W2412272167 hasConcept C105696609 @default.
• W2412272167 hasConcept C1491633281 @default.
• W2412272167 hasConcept C173396325 @default.
• W2412272167 hasConcept C185592680 @default.
• W2412272167 hasConcept C190283241 @default.
• W2412272167 hasConcept C29537977 @default.
• W2412272167 hasConcept C3017707949 @default.
• W2412272167 hasConcept C502942594 @default.
• W2412272167 hasConcept C54355233 @default.
• W2412272167 hasConcept C62112901 @default.
• W2412272167 hasConcept C62478195 @default.
• W2412272167 hasConcept C6929976 @default.
• W2412272167 hasConcept C71924100 @default.
• W2412272167 hasConcept C86803240 @default.
• W2412272167 hasConcept C95444343 @default.
• W2412272167 hasConceptScore W2412272167C104317684 @default.
• W2412272167 hasConceptScore W2412272167C105696609 @default.
• W2412272167 hasConceptScore W2412272167C1491633281 @default.
• W2412272167 hasConceptScore W2412272167C173396325 @default.
• W2412272167 hasConceptScore W2412272167C185592680 @default.
• W2412272167 hasConceptScore W2412272167C190283241 @default.
• W2412272167 hasConceptScore W2412272167C29537977 @default.
• W2412272167 hasConceptScore W2412272167C3017707949 @default.
• W2412272167 hasConceptScore W2412272167C502942594 @default.
• W2412272167 hasConceptScore W2412272167C54355233 @default.
• W2412272167 hasConceptScore W2412272167C62112901 @default.
• W2412272167 hasConceptScore W2412272167C62478195 @default.
• W2412272167 hasConceptScore W2412272167C6929976 @default.
• W2412272167 hasConceptScore W2412272167C71924100 @default.
• W2412272167 hasConceptScore W2412272167C86803240 @default.

• next