Matches in SemOpenAlex for { <https://semopenalex.org/work/W2412630268> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2412630268 abstract "We aimed to assess the efficacy of neoadjuvant chemotherapy followed by surgery (NACT+S), and compared the clinical outcome with that of concurrent chemoradiotherapy (CCRT) in patients with International Federation of Gynecology and Obstetrics (FIGO) IB-IIB cervical cancer.We reviewed 85 patients with FIGO IB-IIB cervical cancer who received NACT+S between 1989 and 2012, and compared them to 358 control patients who received CCRT. The clinical application of NACT was classified based on the following possible therapeutic benefits: increasing resectability after NACT by reducing tumor size or negative conversion of node metastasis; downstaging adenocarcinoma regarded as relatively radioresistant; and preservation of fertility through limited surgery after NACT.Of 85 patients in the NACT+S group, the pathologic downstaging and complete response rates were 68.2% and 22.6%, respectively. Only two young patients underwent limited surgery for preservation of fertility. Patients of the NACT+S group were younger, less likely to have node metastasis, and demonstrated a higher proportion of FIGO IB cases than those of the CCRT group (p≤0.001). The 5-year locoregional control, progression-free survival, and overall survival rates in the NACT+S group were 89.7%, 75.6%, and 92.1%, respectively, which were not significantly different from the rates of 92.5%, 74%, and 84.9% observed in the CCRT group, respectively (p>0.05).NACT+S has no therapeutic advantages over CCRT, the standard treatment. Therefore, NACT+S should be considered only in selected patients through multidisciplinary discussion or clinical trial setting." @default.
- W2412630268 created "2016-06-24" @default.
- W2412630268 creator A5002350066 @default.
- W2412630268 creator A5030066675 @default.
- W2412630268 creator A5039147895 @default.
- W2412630268 creator A5044884424 @default.
- W2412630268 creator A5087447991 @default.
- W2412630268 date "2016-01-01" @default.
- W2412630268 modified "2023-10-18" @default.
- W2412630268 title "Neoadjuvant chemotherapy followed by surgery has no therapeutic advantages over concurrent chemoradiotherapy in International Federation of Gynecology and Obstetrics stage IB-IIB cervical cancer" @default.
- W2412630268 cites W1565051557 @default.
- W2412630268 cites W1971519320 @default.
- W2412630268 cites W1993337480 @default.
- W2412630268 cites W1993479254 @default.
- W2412630268 cites W1995699258 @default.
- W2412630268 cites W2014166989 @default.
- W2412630268 cites W2018336171 @default.
- W2412630268 cites W2055057768 @default.
- W2412630268 cites W2060003507 @default.
- W2412630268 cites W2073305463 @default.
- W2412630268 cites W2096391106 @default.
- W2412630268 cites W2097945491 @default.
- W2412630268 cites W2104522904 @default.
- W2412630268 cites W2123027910 @default.
- W2412630268 cites W2136159512 @default.
- W2412630268 cites W2152292894 @default.
- W2412630268 cites W2314753133 @default.
- W2412630268 cites W2916598930 @default.
- W2412630268 doi "https://doi.org/10.3802/jgo.2016.27.e52" @default.
- W2412630268 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4944019" @default.
- W2412630268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27329200" @default.
- W2412630268 hasPublicationYear "2016" @default.
- W2412630268 type Work @default.
- W2412630268 sameAs 2412630268 @default.
- W2412630268 citedByCount "14" @default.
- W2412630268 countsByYear W24126302682017 @default.
- W2412630268 countsByYear W24126302682018 @default.
- W2412630268 countsByYear W24126302682019 @default.
- W2412630268 countsByYear W24126302682020 @default.
- W2412630268 countsByYear W24126302682021 @default.
- W2412630268 countsByYear W24126302682022 @default.
- W2412630268 countsByYear W24126302682023 @default.
- W2412630268 crossrefType "journal-article" @default.
- W2412630268 hasAuthorship W2412630268A5002350066 @default.
- W2412630268 hasAuthorship W2412630268A5030066675 @default.
- W2412630268 hasAuthorship W2412630268A5039147895 @default.
- W2412630268 hasAuthorship W2412630268A5044884424 @default.
- W2412630268 hasAuthorship W2412630268A5087447991 @default.
- W2412630268 hasBestOaLocation W24126302681 @default.
- W2412630268 hasConcept C121608353 @default.
- W2412630268 hasConcept C126322002 @default.
- W2412630268 hasConcept C141071460 @default.
- W2412630268 hasConcept C143998085 @default.
- W2412630268 hasConcept C146357865 @default.
- W2412630268 hasConcept C151730666 @default.
- W2412630268 hasConcept C2776694085 @default.
- W2412630268 hasConcept C2778220009 @default.
- W2412630268 hasConcept C2778424827 @default.
- W2412630268 hasConcept C29456083 @default.
- W2412630268 hasConcept C509974204 @default.
- W2412630268 hasConcept C71924100 @default.
- W2412630268 hasConcept C86803240 @default.
- W2412630268 hasConceptScore W2412630268C121608353 @default.
- W2412630268 hasConceptScore W2412630268C126322002 @default.
- W2412630268 hasConceptScore W2412630268C141071460 @default.
- W2412630268 hasConceptScore W2412630268C143998085 @default.
- W2412630268 hasConceptScore W2412630268C146357865 @default.
- W2412630268 hasConceptScore W2412630268C151730666 @default.
- W2412630268 hasConceptScore W2412630268C2776694085 @default.
- W2412630268 hasConceptScore W2412630268C2778220009 @default.
- W2412630268 hasConceptScore W2412630268C2778424827 @default.
- W2412630268 hasConceptScore W2412630268C29456083 @default.
- W2412630268 hasConceptScore W2412630268C509974204 @default.
- W2412630268 hasConceptScore W2412630268C71924100 @default.
- W2412630268 hasConceptScore W2412630268C86803240 @default.
- W2412630268 hasIssue "5" @default.
- W2412630268 hasLocation W24126302681 @default.
- W2412630268 hasLocation W24126302682 @default.
- W2412630268 hasLocation W24126302683 @default.
- W2412630268 hasLocation W24126302684 @default.
- W2412630268 hasOpenAccess W2412630268 @default.
- W2412630268 hasPrimaryLocation W24126302681 @default.
- W2412630268 hasRelatedWork W2351245677 @default.
- W2412630268 hasRelatedWork W2370148199 @default.
- W2412630268 hasRelatedWork W2376116016 @default.
- W2412630268 hasRelatedWork W2376593068 @default.
- W2412630268 hasRelatedWork W2384708512 @default.
- W2412630268 hasRelatedWork W2404042595 @default.
- W2412630268 hasRelatedWork W2404402449 @default.
- W2412630268 hasRelatedWork W3030201060 @default.
- W2412630268 hasRelatedWork W4245694863 @default.
- W2412630268 hasRelatedWork W4308718010 @default.
- W2412630268 hasVolume "27" @default.
- W2412630268 isParatext "false" @default.
- W2412630268 isRetracted "false" @default.
- W2412630268 magId "2412630268" @default.
- W2412630268 workType "article" @default.